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Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults.

Author: BurtonMartin J, HeadKaren, NaessensKatrien, PluggeEmma, SutherlandAnna, WareLynda, WeeBee

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Oral olanzapine, when used as an antiemetic for cancer patients, likely doubles the chance of not experiencing nausea or vomiting during chemotherapy compared to placebo. However, it may increase the risk of other adverse events, particularly somnolence and fatigue.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Olanzapine as an antiemetic represents a new use of an antipsychotic drug. People with cancer may experience nausea and vomiting whilst receiving chemotherapy or radiotherapy, or whilst in the palliative phase of illness. OBJECTIVES: To assess the efficacy and safety of olanzapine when ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513437/

データ提供：米国国立医学図書館（NLM）

Olanzapine: A New Oasis in the Desert of Nausea and Vomiting

For patients undergoing [cancer treatment], [nausea and vomiting] can be a debilitating side effect, making the journey through treatment even more challenging. Researchers are constantly searching for new and effective ways to manage these symptoms, seeking an oasis of relief in the desert of discomfort.

This study investigated the use of [olanzapine], a drug typically used to treat [mental health conditions], as an antiemetic to prevent or treat [nausea and vomiting] associated with [cancer treatment].

The researchers found that [olanzapine] was effective in reducing [nausea and vomiting], offering a potential new treatment option for patients.

Olanzapine: A Promising Antiemetic

The study showed that [olanzapine] was effective in reducing [nausea and vomiting] in patients undergoing [cancer treatment], suggesting a potential new role for this drug in managing these debilitating symptoms.

Implications for Cancer Treatment

This research offers hope for patients undergoing [cancer treatment] by providing a potential new weapon in the fight against [nausea and vomiting]. By understanding the potential benefits and risks of [olanzapine], doctors can make more informed decisions about treatment strategies for their patients.

Dr.Camel's Conclusion

The desert of [cancer treatment] can be a harsh and unforgiving place, but this study offers a glimmer of hope in the form of [olanzapine]. This research suggests that [olanzapine] may be a valuable tool for managing [nausea and vomiting] in patients undergoing [cancer treatment], potentially improving their quality of life during this challenging journey. As a researcher, I am encouraged by the ongoing search for new and innovative ways to alleviate the suffering of patients.

Date :
  1. Date Completed 2018-10-24
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

30246876

DOI: Digital Object Identifier

PMC6513437

Related Literature

Article Analysis
・Effective treatment of nausea
SNS
PICO Info
in preparation
Languages

English

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