Early Targeted Combination Treatment With Conventional Synthetic Disease-Modifying Antirheumatic Drugs and Long-Term Outcomes in Rheumatoid Arthritis: Ten-Year Follow-Up Results of a Randomized Clinical Trial.

Author: , HannonenPekka, JulkunenHeikki, Kaipiainen-SeppänenOili, KauppiMarkku J, KautiainenHannu, KoskiJuhani, LaasonenLeena, Leirisalo-RepoMarjatta, MalmiTimo, MöttönenTimo, RantalaihoVappu, SandströmTia, UutelaToini, Yli-KerttulaTimo

Paper Details 
Original Abstract of the Article :
The short-term outcomes of remission-targeted treatments of rheumatoid arthritis (RA) are well-established, but the long-term success of such strategies is speculative, as is the role of early add-on biologics. We assessed the 10-year outcomes of patients with early RA treated with initial remission...See full text at original site
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引用元:
https://doi.org/10.1002/acr.23782

データ提供:米国国立医学図書館(NLM)

Early Targeted Combination Treatment: A Sandstorm of Hope for Rheumatoid Arthritis

The world of rheumatology is constantly striving to find effective treatments for debilitating conditions like rheumatoid arthritis (RA). This study investigates the long-term outcomes of a remission-targeted triple combination therapy for early RA, providing valuable insights into the potential for achieving sustained remission. The researchers followed patients with early RA for 10 years, comparing the long-term effects of a triple combination therapy involving conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), prednisolone, and either infliximab (IFX) or placebo. The study's findings highlight the potential benefits of early and aggressive treatment strategies, emphasizing the importance of achieving remission as early as possible to improve long-term outcomes.

A Oasis of Remission: The Promise of Early Intervention in RA

This research provides a beacon of hope for patients with early RA, demonstrating the potential for achieving sustained remission with an aggressive treatment approach. The study's findings, like a cool spring in the desert, suggest that early intervention can significantly impact the long-term course of the disease. The results emphasize the importance of working closely with healthcare professionals to develop personalized treatment plans aimed at achieving remission as early as possible.

Navigating the Sands of Rheumatoid Arthritis: Early Treatment and Long-Term Outcomes

The study's findings emphasize the significance of early and aggressive treatment strategies in RA. It's like navigating a challenging desert journey – the earlier you start, the better your chances of successfully reaching your destination. This research underscores the importance of seeking medical attention early and working closely with healthcare professionals to develop a personalized treatment plan that can help mitigate the impact of RA on your life.

Dr.Camel's Conclusion

This study offers a valuable insight into the long-term outcomes of early and aggressive treatment strategies for rheumatoid arthritis. Like a caravan traversing the desert, early intervention can help patients navigate the challenges of this debilitating condition and achieve a more favorable outcome. The research serves as a reminder that early and aggressive treatment strategies can significantly impact the long-term course of RA.

Date :
  1. Date Completed 2020-04-10
  2. Date Revised 2020-04-10
Further Info :

Pubmed ID

30295425

DOI: Digital Object Identifier

10.1002/acr.23782

Related Literature

SNS
PICO Info
in preparation
Languages

English

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