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Epidermal growth factor receptor blockers for the treatment of ovarian cancer.

Author: BryantAndrew, GaitskellKezia, GoodallRichard J, LyonsThomas J, MorrisonJo, ThomaClemens, WiggansAlison J

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Epithelial ovarian cancer (EOC) is a common cause of death from cancer in women worldwide. While surgery and chemotherapy are used to treat the disease, many women experience a return of the cancer within two years. New medications that target specific proteins, like those that block epidermal growth factor receptor (EGFR), are being developed to improve treatment outcomes.
Paper Details　
Original Abstract of the Article :
This is an update of a previously published version of the review (Issue 10, 2011).Epithelial ovarian cancer (EOC) is the seventh most common cause of cancer death among women worldwide. Treatment consists of a combination of surgical debulking and platinum-based chemotherapy. Between 55% and 75% of...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430330/

データ提供：米国国立医学図書館（NLM）

Epidermal Growth Factor Receptor Blockers: Potential Treatment for Ovarian Cancer

The fight against [epithelial ovarian cancer (EOC)] is an ongoing challenge in the field of [oncology]. This review explores the potential of [epidermal growth factor receptor (EGFR) blockers] in the treatment of [EOC]. The review examines the [molecular basis] of [EOC] and the role of [EGFR] in this disease, evaluating the potential of [EGFR blockers] as [therapeutic agents].

EGFR Blockers Offer Potential for Targeted Therapy

The review highlights the development of [novel agents] targeting [EGFR], including [EGFR tyrosine kinase inhibitors] and [anti-EGFR antibodies]. These agents offer a potential avenue for [targeted therapy] in [EOC], aiming to improve [treatment outcomes]. Further research is needed to evaluate the efficacy and safety of [EGFR blockers] in [EOC] and to determine their optimal role in [treatment strategies].

Implications for EOC Treatment and Future Research

This review underscores the importance of [molecular-based approaches] in [EOC treatment]. The development of [EGFR blockers] represents a promising advancement in [targeted therapy] for [EOC]. Continued research is essential to evaluate the clinical potential of these agents and to optimize their use in [EOC treatment]. Like a camel traversing a vast and often treacherous desert, the fight against EOC requires persistence, innovation, and a commitment to exploring new pathways to treatment.

Dr. Camel's Conclusion

This review is like a desert oasis, offering a glimmer of hope in the fight against EOC. The development of EGFR blockers represents a promising new weapon in our arsenal, bringing us closer to a future where EOC can be effectively managed and treated. As researchers, we must continue to explore the intricate mechanisms of this disease and strive for a world where individuals with EOC can receive timely and effective care.
Date :
  1. Date Completed 2019-02-13
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

30321910

DOI: Digital Object Identifier

PMC6430330

SNS
PICO Info
in preparation
Languages

English

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