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A comparative study of cholecalciferol, dihydrotachysterol and alfacalcidol in the treatment of elderly patients with hypocalcaemia.

Author: ColesJ A, DowneyL J, HamdyR C

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effectiveness of three treatments for low calcium levels in 50 elderly patients. All treatments (dihydrotachysterol, cholecalciferol, and alfacalcidol) were successful in restoring normal calcium levels within two weeks. While alfacalcidol caused high calcium levels in some patients, this resolved quickly after stopping the medication. Dihydrotachysterol and cholecalciferol did not cause high calcium levels, requiring less frequent monitoring. A single injection of cholecalciferol also eliminates the need for consistent medication taking.
Paper Details　
Original Abstract of the Article :
Fifty elderly patients with hypocalcaemia were randomly treated for 8 weeks with either oral dihydrotachysterol, parenteral cholecalciferol or oral alfacalcidol. All three treatments were successful in normalizing the serum calcium levels in most patients within 2 weeks. Hypercalcaemia was seen only...See full text at original site
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引用元：
https://doi.org/10.1093/ageing/16.3.178

データ提供：米国国立医学図書館（NLM）

Treating Hypocalcemia in Elderly Patients: A Comparative Study of Vitamin D Analogs

Hypocalcemia, a condition where calcium levels in the blood are too low, can be a challenging health issue, especially for elderly individuals. This study compares the effectiveness and safety of different vitamin D analogs (dihydrotachysterol, cholecalciferol, and alfacalcidol) in treating hypocalcemia in elderly patients. The study found that all three treatments were successful in normalizing calcium levels in most patients, but alfacalcidol was more likely to cause hypercalcemia, highlighting the importance of careful monitoring and individualized treatment approaches for elderly patients with hypocalcemia.

Navigating the Calcium Balance: A Comparative Study of Vitamin D Analogs

The study's findings are like a camel caravan navigating a delicate balance between two extremes, ensuring that calcium levels remain within a healthy range. The researchers compared the effectiveness of different vitamin D analogs, carefully observing their impact on calcium levels. The results offer valuable insights into the nuances of vitamin D analog therapy for hypocalcemia in elderly patients, emphasizing the need for personalized treatment plans and careful monitoring.

Calcium and the Elderly: Finding the Right Balance

This research highlights the importance of individualized treatment approaches for hypocalcemia in elderly patients. Just as a camel caravan adapts its pace and strategy based on the terrain, healthcare providers need to carefully consider the specific needs of each elderly patient with hypocalcemia. This study provides valuable information for choosing the most appropriate vitamin D analog and monitoring treatment effectively.

Dr. Camel's Conclusion

This study demonstrates the importance of carefully considering the risks and benefits of different vitamin D analogs when treating hypocalcemia in elderly patients. It's like a camel caravan choosing the right path through the desert, ensuring that the journey is safe and effective.

Date :
  1. Date Completed 1987-08-03
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3037863

DOI: Digital Object Identifier

10.1093/ageing/16.3.178

Related Literature

Article Analysis
・Effective treatment of calcium
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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