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Cutaneous adverse drug reactions to psychotropic drugs and their risk factors - a case-control study.

Author: BleichStefan, BridlerRené, GreilWaldemar, GrohmannRenate, HaslerGregor, KasperSiegfried, StassenHans, TotoSermin, ZhangXueqiong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cutaneous adverse drug reactions (CADRs) were more prevalent in patients treated with clomipramine, maprotiline, carbamazepine, lamotrigine, acamprosate, clomethiazole, and disulfiram. Women were more vulnerable to CADRs, especially those under 50 years of age.
Paper Details　
Original Abstract of the Article :
Cutaneous adverse drug reactions (CADRs) in patients with psychotropic drugs are common. Large studies on the relevant drugs and other risk factors are still scarce. 594 cases of severe CADRs ("cases") were compared with 8085 cases of other adverse drug reactions ("non-cases") documented in a pharma...See full text at original site
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引用元：
https://doi.org/10.1016/j.euroneuro.2018.10.010

データ提供：米国国立医学図書館（NLM）

Skin Reactions: The Desert of Psychotropic Medications

This research, like a careful explorer navigating a vast desert of psychotropic medications, investigates the prevalence and risk factors of cutaneous adverse drug reactions (CADRs). The researchers, armed with a pharmacovigilance program, meticulously analyzed data from thousands of patients, seeking to uncover the reasons behind these skin reactions.

The Desert of Skin Reactions: Risk Factors Unveiled

The study identified several risk factors for CADRs, including female sex, substance abuse, and specific medications like maprotiline, carbamazepine, and lamotrigine. It's like finding a hidden map through the desert, revealing the pathways that lead to these adverse reactions. This knowledge is crucial for clinicians to understand and mitigate the risks associated with these medications.

Navigating the Desert: Patient Safety and Awareness

This research, like a beacon of light in the desert of potential side effects, emphasizes the importance of patient safety and awareness. Clinicians should be vigilant in monitoring for CADRs, especially in women during their reproductive years. It's like providing a reliable guide to travelers in the desert, ensuring their safety and well-being.

Dr. Camel's Conclusion

This study, like a weathered scroll containing ancient medical wisdom, highlights the importance of understanding the nuances of psychotropic medication use. It underscores the need for careful monitoring and awareness of potential side effects, especially CADRs. As we continue our journey through the desert of drug discovery, let's prioritize patient safety and empower individuals to make informed decisions about their health.

Date :
  1. Date Completed 2019-08-05
  2. Date Revised 2019-08-05
Further Info :

Pubmed ID

30424913

DOI: Digital Object Identifier

10.1016/j.euroneuro.2018.10.010

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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