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A prospective randomized comparative study to determine appropriate edoxaban administration period, to prevent deep vein thromboembolism in patients with total knee arthroplasty.

Author: HashimotoShingo, HayashiShinya, IshidaKazunari, KodatoKazuki, KurodaRyosuke, KurosakaMasahiro, MatsumotoTomoyuki, MatsushitaTakehiko, NiikuraTakahiro, SasakiHiroshi, ShibanumaNao, TakayamaKoji, TodaAkihiko

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Edoxaban 15 mg administered for 2 weeks was more effective in preventing deep vein thrombosis (DVT) after total knee arthroplasty (TKA) than when administered for 1 week. There was no significant difference in DVT incidence at 1 week, but the 2-week group had a significantly lower incidence at 2 weeks.
Paper Details　
Original Abstract of the Article :
BACKGROUND: This study aimed to determine the appropriate administration duration of edoxaban 15 mg (a factor Xa inhibitor) for the prevention of deep vein thrombosis (DVT) after total knee arthroplasty (TKA). METHODS: Our study comprised 202 patients who underwent TKA (excluding bilateral TKA) at ...See full text at original site
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引用元：
https://doi.org/10.1016/j.jos.2018.06.004

データ提供：米国国立医学図書館（NLM）

Preventing Deep Vein Thrombosis After Total Knee Arthroplasty: Edoxaban's Effectiveness

This study embarks on a journey through the realm of post-surgical care, investigating the optimal duration of edoxaban administration for preventing deep vein thrombosis (DVT) after total knee arthroplasty (TKA). Like skilled surgeons navigating a complex procedure, researchers sought to find the most effective way to minimize the risk of DVT, a potentially serious complication. This study is like a surgical scalpel, meticulously dissecting the intricacies of post-TKA care to identify the optimal treatment approach.

Edoxaban: A Powerful Tool for DVT Prevention

The study's findings suggest that edoxaban administration for two weeks is more effective in preventing DVT after TKA compared to one week of administration. This research provides valuable insights for healthcare professionals, offering a more precise and effective strategy for managing DVT risk in patients undergoing TKA.

A Safer Journey Through Recovery

This research highlights the importance of optimizing treatment strategies for preventing DVT after TKA, emphasizing the potential of edoxaban for enhancing patient safety and recovery. The study's findings are like a protective shield, guarding against the potential dangers of DVT and paving the way for a smoother and safer journey through recovery for patients undergoing TKA.

Dr. Camel's Conclusion

This study takes us on a journey through the intricate procedures of total knee arthroplasty (TKA), revealing the effectiveness of edoxaban in preventing deep vein thrombosis (DVT). Like a skilled desert guide, researchers navigated the complex terrain of post-surgical care, uncovering the optimal duration of edoxaban administration. This research offers a valuable tool for minimizing the risk of DVT, ensuring a smoother and safer recovery for patients undergoing TKA.

Date :
  1. Date Completed 2019-06-04
  2. Date Revised 2019-06-04
Further Info :

Pubmed ID

30431004

DOI: Digital Object Identifier

10.1016/j.jos.2018.06.004

Related Literature

Article Analysis
・Side Effects of edoxaban
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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