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Intravenous acyclovir therapy of first episodes of genital herpes: a multicenter double-blind, placebo-controlled trial.

Author: BrysonY J, DurackD T, Friedman-KienA E, GnannJ W, KaplowitzL G, KleinR J, LovettM, PeacockJ E, SparlingP F, WhitleyR J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study investigated the effectiveness and safety of intravenous acyclovir in treating first-time genital herpes outbreaks. The study aimed to confirm previous findings, assess the impact of intravenous acyclovir on future outbreaks, and gain a better understanding of the natural course of genital herpes.
Paper Details　
Original Abstract of the Article :
A collaborative multicenter double-blind, placebo-controlled trial of intravenous acyclovir treatment of first-episode genital herpes was performed in order to substantiate previous findings on the efficacy and safety of this drug, to evaluate the influence of parenteral therapy on recurrence freque...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(88)90578-5

データ提供：米国国立医学図書館（NLM）

Intravenous Acyclovir for Genital Herpes

The world of herpes simplex virus (HSV) infection is a vast and sometimes perplexing landscape, with ongoing research seeking to better understand and manage this prevalent condition. This study explores the efficacy and safety of intravenous acyclovir treatment for first-episode genital herpes, evaluating its impact on recurrence frequency. The authors present a multicenter, double-blind, placebo-controlled trial, providing robust evidence for the effectiveness of intravenous acyclovir in managing this common infection.

Acyclovir: A Promising Treatment

This study provides strong evidence for the efficacy of intravenous acyclovir in managing first-episode genital herpes, offering a valuable treatment option for individuals experiencing this condition. The results underscore the importance of early intervention in managing HSV infections, potentially reducing the likelihood of recurrence.

Managing Herpes Simplex Virus

This research highlights the importance of utilizing evidence-based treatments for managing HSV infections. The study's findings emphasize the need for understanding the benefits and potential drawbacks of different treatment approaches, ensuring appropriate and effective care for individuals experiencing HSV outbreaks.

Dr.Camel's Conclusion

This research, like a camel seeking a refreshing oasis amidst the arid landscape of HSV infection, offers a valuable treatment option. The study's findings underscore the importance of utilizing evidence-based approaches to manage this common infection. By continuing to explore the complexities of HSV, we can illuminate pathways to better manage this condition, allowing individuals to navigate its challenges with greater ease and well-being.

Date :
  1. Date Completed 1988-10-03
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3046350

DOI: Digital Object Identifier

10.1016/0002-9343(88)90578-5

Related Literature

Article Analysis
・Effective treatment of genital herpes
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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