Five-Year Follow-up of Nonfibrotic Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials.

Author: , DanielEbenezer, DunaiefJoshua L, FerrisFrederick, GrunwaldJuan E, JaffeGlenn J, KimBenjamin J, MaguireMaureen G, MartinDaniel F, PanWei, TothCynthia A, YingGui-Shuang

Paper Details 
Original Abstract of the Article :
PURPOSE: To describe changes in visual acuity (VA) and macular morphologic features at 5 years in eyes with nonfibrotic scar (NFS) identified at 1 year in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). DESIGN: Prospective cohort study within a randomized clinical trial...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30476517

データ提供:米国国立医学図書館(NLM)

The Desert of Age-Related Macular Degeneration: Tracking the Long-Term Effects of Treatment

Imagine a desert landscape, where the delicate structures of the eye are subject to the harsh effects of age-related macular degeneration (AMD). This research takes a long-term perspective, tracking the visual outcomes of patients with nonfibrotic scars (NFS) five years after receiving anti-VEGF treatment for AMD. The researchers are like seasoned desert explorers, carefully documenting the changes in the delicate ecosystem of the eye over time.

A Glimpse into the Future: The Long-Term Effects of Treatment

The research revealed that while NFS may initially provide a promising outlook, it's not a guarantee of long-term visual stability. It's like discovering a hidden oasis in the desert, but realizing that it might not be a permanent source of water. The researchers found that 28% of eyes with NFS developed fibrotic scars within five years. This underscores the importance of ongoing monitoring and potential adjustments in treatment plans to ensure optimal visual outcomes.

Navigating the Desert of AMD: A Journey of Hope and Vigilance

The study highlights the complex and often unpredictable nature of AMD, emphasizing the need for ongoing research and vigilance in managing this condition. It's like navigating a challenging desert landscape, where careful observation and continuous adaptation are essential for survival. The researchers offer valuable insights into the long-term effects of treatment, guiding clinicians and patients in their journey through the desert of AMD.

Dr.Camel's Conclusion

This research provides a valuable roadmap for navigating the complex terrain of AMD treatment. It's like being a guide in the desert, offering valuable insights and strategies for navigating this challenging journey. By understanding the long-term effects of treatment and embracing a proactive approach to management, we can help patients preserve their vision and navigate the desert of AMD with greater confidence and hope.

Date :
  1. Date Completed 2020-01-30
  2. Date Revised 2023-10-11
Further Info :

Pubmed ID

30476517

DOI: Digital Object Identifier

NIHMS998213

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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