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Efficacy and side effects of magnesium sulfate and ritodrine as tocolytic agents.

Author: BerkowitzG S, BerkowitzR L, LynchL, MehalekK E, WilkinsI A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ritodrine and magnesium sulfate were both effective in delaying delivery in 120 patients with established preterm labor. The two drugs had comparable efficacy, with side effects being more serious in the ritodrine group.
Paper Details　
Original Abstract of the Article :
Ritodrine as the first-line drug in the treatment of established preterm labor has been supplanted in some centers by magnesium sulfate. To assess the relative efficacy and rates of side effects of these two agents, 120 patients were randomly assigned to receive one of these two drugs. Patients were...See full text at original site
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引用元：
https://doi.org/10.1016/s0002-9378(88)80035-8

データ提供：米国国立医学図書館（NLM）

Comparing Tocolytics for Preterm Labor: A Camel's Perspective

The field of [obstetrics] is always striving to find the best way to help mothers and babies. This study dives into the use of [tocolytic drugs] to delay delivery in cases of [preterm labor]. The researchers used a [randomized controlled trial] to compare the effectiveness and side effects of [magnesium sulfate] and [ritodrine]. They discovered that both drugs were remarkably successful in delaying delivery by more than 48 hours, with [96.3%] of patients receiving [ritodrine] and [92.3%] of patients receiving [magnesium sulfate] achieving this goal. While both drugs were effective, they observed more serious side effects in the group receiving [ritodrine]. The authors emphasize that both medications are valuable tools for [obstetricians] to manage [preterm labor] effectively.

Two Tocolytics: A Tale of Two Camels

This study provides a beacon of hope for mothers facing the challenges of [preterm labor]. The fact that both [magnesium sulfate] and [ritodrine] were effective in delaying delivery, giving precious time for fetal development, is a significant victory. The study also highlights the importance of individualizing treatment plans, as the side effect profile can differ between patients.

Tocolytics and the Camel's Journey: Navigating the Sands of Premature Birth

This research underscores the importance of understanding the potential benefits and risks of [tocolytic medications]. It reminds us that each patient is unique and requires individualized care. With the right approach, we can help mothers and their babies navigate the challenges of [preterm labor] with greater confidence.

Dr.Camel's Conclusion

This research highlights the progress made in treating preterm labor. While both magnesium sulfate and ritodrine are effective tocolytics, doctors must carefully consider the individual patient to determine the best course of treatment.

Date :
  1. Date Completed 1988-10-18
  2. Date Revised 2019-06-15
Further Info :

Pubmed ID

3048103

DOI: Digital Object Identifier

10.1016/s0002-9378(88)80035-8

Related Literature

Article Analysis
・Side Effects of magnesium sulfate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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