Oral small molecules for the treatment of atopic dermatitis: a systematic review.

Author: Atanaskova MesinkovskaNatasha, Heydari SeradjMehran, JuhaszMargit, MobasherPezhman, RaffiJodie

Paper Details 
Original Abstract of the Article :
<b>Introduction</b>: Atopic dermatitis (AD) is a chronic, inflammatory skin disease. Conventional treatments include topical emollients, corticosteroids, calcineurin inhibitors, phototherapy, and systemic immunomodulatory agents, however, these medications have limitations in the treatment of moder...See full text at original site
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引用元:
https://doi.org/10.1080/09546634.2018.1544412

データ提供:米国国立医学図書館(NLM)

Oral Small Molecules: A Promising New Frontier in Atopic Dermatitis Treatment

The world of dermatology is constantly evolving, and the treatment of atopic dermatitis (AD) is no exception. This research delves into the potential of oral small molecules as a novel therapeutic approach for AD. It's like a camel caravan venturing into a new oasis in the vast desert of dermatological research. The researchers embarked on a comprehensive journey, scouring the literature for studies on oral small molecules and their effectiveness in managing AD. Their meticulous investigation led them to a promising conclusion.

Oral Small Molecules Show Potential for Treating Atopic Dermatitis

This study reveals that oral small molecules like apremilast, baricitinib, JNJ-39758979, and tofacitinib hold significant promise for AD treatment. These molecules demonstrated a positive impact on AD disease scores, patient-reported outcomes, and overall quality of life. It's like finding a hidden spring of relief amidst the scorching sands of chronic skin inflammation.

A New Hope for Patients with Atopic Dermatitis

These findings offer a beacon of hope for individuals battling AD. The prospect of effective oral treatment options, potentially leading to reduced reliance on topical medications, is a welcome development. However, as with any new discovery, further research is crucial to confirm the long-term efficacy and safety of these oral small molecules. It's like carefully analyzing the water in a new oasis before deciding whether to settle down there.

Dr.Camel's Conclusion

This study sheds light on the potential of oral small molecules in treating AD. While more research is needed, this could be a game-changer for patients seeking effective and manageable treatment options. It's like finding a promising route through the desert, leading towards a more comfortable and enjoyable journey for those living with AD.

Date :
  1. Date Completed 2019-11-25
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

30501539

DOI: Digital Object Identifier

10.1080/09546634.2018.1544412

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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