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[Pharmacokinetic and clinical studies of ceftizoxime in the perinatal period. The Chemotherapy Research Group for Mothers and Children].

Author: ChoN, FujiiR, IchinoeK, MatsudaS, NinomiyaK, NodaK, OkadaH, OsanoM, ShimizuT, YoshiokaH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Ceftizoxime (CZX) was safe and effective for the treatment and prophylaxis of infection in the perinatal period in 29 patients. The drug crossed the placenta and reached therapeutic levels in fetal circulation. No side effects were observed in 44 cases.
Paper Details　
Original Abstract of the Article :
Pharmacokinetic and clinical studies of ceftizoxime (CZX) in the perinatal period gave the following results: 1. Peak concentrations of CZX in the maternal serum, umbilical cord serum and amniotic fluid in mothers after one intravenous injection of 1 g were, respectively, 70.2 micrograms/ml at 0 hou...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3050193

データ提供：米国国立医学図書館（NLM）

Ceftizoxime: A Safe and Effective Treatment for Perinatal Infections

Perinatal infections, infections that occur during pregnancy or childbirth, can pose a serious risk to both mother and child. This study investigates the safety and efficacy of ceftizoxime (CZX), an antibiotic, in treating perinatal infections. Researchers conducted pharmacokinetic and clinical studies to evaluate CZX's distribution in the body and its effectiveness in treating infections. Their findings demonstrate that CZX is a safe and effective treatment option for perinatal infections, with a high efficacy rate and minimal side effects.

Hope for Mothers and Children: A Safe Antibiotic for Perinatal Infections

The study showed that CZX is well tolerated by both mothers and their newborns, with minimal side effects. This is encouraging news for parents facing the challenge of perinatal infections. The high efficacy rate of CZX in treating and preventing perinatal infections provides valuable reassurance for both mothers and their healthcare providers.

Protecting the Vulnerable: Navigating Perinatal Infections

Perinatal infections can be a significant concern, but this study demonstrates that CZX offers a safe and effective treatment option. If you're facing a perinatal infection, consult your doctor to discuss potential treatment options and the benefits of CZX.

Dr. Camel's Conclusion

This research offers a ray of hope for mothers and children facing the challenges of perinatal infections. Like a desert oasis providing life-sustaining water, CZX offers a safe and effective treatment option, ensuring the well-being of both mother and child.

Date :
  1. Date Completed 1988-11-23
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3050193

DOI: Digital Object Identifier

3050193

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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