Comparison of the effects of peramivir and oseltamivir on the rise in platelet count in patients with or without proven influenza
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Author: KimYoung-Gon, KoSun-Young, LeeSung Woo

Paper Details 
Original Abstract of the Article :
Neuraminidase (sialidase) inhibitors are considered to delay platelet clearance through the inhibition of platelet desialylation. A novel neuraminidase inhibitor, peramivir, was recently approved for intravenous administration by the US FDA. We aimed to compare the effects of peramivir and oseltamiv...See full text at original site
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引用元:
https://doi.org/10.5414/CP203366

データ提供:米国国立医学図書館(NLM)

Neuraminidase Inhibitors: A Tale of Two Drugs

The field of [Influenza treatment] is constantly searching for new and effective therapies. This research compares the effects of two neuraminidase inhibitors, [peramivir] and [oseltamivir], on platelet counts in patients with and without proven influenza. The authors investigated the potential impact of these drugs on platelet clearance, a process that can be influenced by neuraminidase inhibitors. The study found that both peramivir and oseltamivir had an impact on platelet counts, suggesting a potential effect on platelet desialylation.

Understanding Platelet Counts: A Complex Picture

The study found that both [peramivir] and [oseltamivir] had an impact on platelet counts, suggesting their potential to affect the desialylation process, a key step in platelet clearance. It's important to note that further research is needed to fully understand the mechanisms involved and to clarify the clinical significance of these findings.

Navigating Influenza: A Cautious Approach

The study highlights the potential impact of neuraminidase inhibitors on platelet counts, suggesting a need for caution when using these medications, especially in individuals with pre-existing platelet disorders. As a wise camel, I always recommend consulting with a healthcare professional to discuss any potential risks or concerns associated with medications, particularly during times of illness.

Dr.Camel's Conclusion

This research delves into the complex world of neuraminidase inhibitors, providing insights into their potential impact on platelet counts. It emphasizes the importance of ongoing research to better understand the mechanisms involved and to ensure the safe and effective use of these medications. As a wise camel, I encourage you to approach your health with awareness and consult with a healthcare professional for personalized guidance.

Date :
  1. Date Completed 2019-08-05
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

30526812

DOI: Digital Object Identifier

10.5414/CP203366

Related Literature

SNS
PICO Info
in preparation
Languages

English

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