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Plecanatide for Treatment of Chronic Constipation and Irritable Bowel Syndrome.

Author: LoveBryan L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Plecanatide is a new medication that stimulates a receptor in the gut to increase water secretion and soften stools. It is approved by the FDA to treat chronic idiopathic constipation and irritable bowel syndrome with constipation.
Paper Details　
Original Abstract of the Article :
Chronic idiopathic constipation and irritable bowel syndrome with constipation are commonly encountered in ambulatory patients, but limited options exist for patients with persistent or severe symptoms following treatment with nonprescription products. Plecanatide (Trulance, Synergy Pharmaceuticals,...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.amjmed.2018.11.027

データ提供：米国国立医学図書館（NLM）

Plecanatide: A New Oasis for Chronic Constipation

Chronic constipation, like a troublesome sandstorm, can disrupt daily life. This study, like a caravan seeking a path through the desert, explores the potential of plecanatide, a guanylate cyclase-C receptor agonist, to alleviate chronic constipation. The authors delve into the mechanism of action of this peptide analog, highlighting its ability to increase chloride and bicarbonate secretion in the intestine, promoting water movement into the gut lumen and facilitating bowel movements. Plecanatide, like a gentle breeze, offers a new approach to treating chronic constipation and irritable bowel syndrome with constipation, potentially providing a smoother journey through the desert of digestive discomfort.

Plecanatide: A New Path Through the Desert of Constipation

This research is a promising step forward in the treatment of chronic constipation. Plecanatide offers a new and effective approach to this common condition, potentially providing relief for millions of people struggling with this uncomfortable ailment.

Plecanatide: A Refreshing Oasis for Gut Health

Chronic constipation can have a significant impact on overall health and well-being. This study offers a glimmer of hope for individuals seeking relief from this condition. Remember to consult with your doctor to determine if plecanatide is the right solution for you.

Dr.Camel's Conclusion

Plecanatide is a promising oasis in the desert of chronic constipation. Its unique mechanism of action offers a new and effective approach to treating this common condition. This research is a reminder that even in the vast landscape of medicine, there are always new discoveries waiting to be made.

Date :
  1. Date Completed 2020-01-07
  2. Date Revised 2020-01-07
Further Info :

Pubmed ID

30550753

DOI: Digital Object Identifier

10.1016/j.amjmed.2018.11.027

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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