Paper Details

  1. Home
  2. Paper Details

Vitamin D Daily versus Monthly Administration: Bone Turnover and Adipose Tissue Influences.

Author: Dalle CarbonareLuca, Del FornoFrancesco, PiacentiniGiorgio, PietrobelliAngelo, ValentiMaria Teresa

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Vitamin D plays a role in bone health and other conditions, including digestive problems, heart disease, cancer, and autoimmune diseases. This study compared the effects of taking vitamin D daily versus monthly to achieve the same total dose in people with low vitamin D levels. Both approaches were found to be effective in raising vitamin D levels, and taking a large monthly dose led to faster improvements compared to a daily dose. After 18 months of monthly treatment, vitamin D levels were normal, calcium levels increased, and bone turnover decreased. Interestingly, people with larger waists had lower vitamin D levels at the start of the study.
Paper Details　
Original Abstract of the Article :
Vitamin D is involved in bone metabolism and in many various extra-skeletal diseases such as malabsorption syndromes, cardiovascular and metabolic diseases, cancer, and autoimmune and neurological diseases. However, data on the optimal route of administration are not consistent. The aims of our stud...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315364/

データ提供：米国国立医学図書館（NLM）

Vitamin D: A Multifaceted Nutrient with a Dose of Mystery

Vitamin D plays a crucial role in [bone health] and numerous other physiological processes. This research investigates the optimal [route of administration] for vitamin D, comparing [daily vs. monthly administration] in a cohort of adults with [low levels of 25(OH) vitamin D3]. The authors analyzed the effects of these different regimens on [bone turnover, bone metabolism, and adipose tissue] over a period of six months.

Unveiling the Secrets of Vitamin D Administration

This study aimed to determine whether daily or monthly administration of vitamin D is more effective in correcting [hypovitaminosis D] and maintaining adequate levels. The researchers found that both regimens were equally effective in raising vitamin D levels, with [36 out of 44 patients] achieving normal levels after six months. Interestingly, they observed a correlation between [waist circumference] and baseline vitamin D levels, suggesting a potential link between vitamin D status and [adipose tissue].

A Journey Through the Desert of Vitamin D Research

This research adds valuable insights into the optimal approach to vitamin D supplementation. The findings suggest that monthly administration may be just as effective as daily dosing, potentially improving patient compliance and convenience. The study also highlights the importance of considering [waist circumference] as a potential indicator of vitamin D status. It's like navigating a vast desert of vitamin D research, seeking to understand the best ways to maintain this crucial nutrient.

Dr.Camel's Conclusion

The study suggests that both daily and monthly administration of vitamin D can be effective in correcting hypovitaminosis D. The finding that monthly administration may be equally effective could improve patient compliance and convenience. Further research is needed to fully understand the long-term effects of both regimens and to explore the potential link between vitamin D status and waist circumference.

Date :
  1. Date Completed 2019-02-04
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

30563215

DOI: Digital Object Identifier

PMC6315364

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.