Augmentation agents to serotonin reuptake inhibitors for treatment-resistant obsessive-compulsive disorder: A network meta-analysis.

Author: AiMing, ChenXiao-Rong, KuangLi, LiDa-Qi, LiYao, LvZhen, WanLi-Yang, WangGao-Mao, WangWo, ZhangKai-Fu, ZhouDong-Dong, ZhouXiao-Xin

Paper Details 
Original Abstract of the Article :
BACKGROUND: Various agents for augmentation of serotonin reuptake inhibitors have been investigated for treatment-resistant obsessive-compulsive disorder (OCD). We aimed to comprehensively compare different augmentation agents for treatment-resistant OCD in adults. METHODS: PubMed, Embase, Web of S...See full text at original site
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引用元:
https://doi.org/10.1016/j.pnpbp.2018.12.009

データ提供:米国国立医学図書館(NLM)

Augmenting Serotonin Reuptake Inhibitors for Treatment-Resistant OCD: A Network Meta-analysis

Obsessive-compulsive disorder (OCD), characterized by persistent intrusive thoughts and repetitive behaviors, can significantly impact quality of life. This network meta-analysis examines the efficacy of various augmentation agents for serotonin reuptake inhibitors (SSRIs) in treating treatment-resistant OCD. The researchers conducted a comprehensive review of existing studies, comparing the effectiveness of different augmentation agents in reducing OCD symptoms. Their findings provide valuable insights into the potential benefits and limitations of various augmentation strategies for treatment-resistant OCD, informing clinical decision-making and improving patient care.

Finding Relief for Treatment-Resistant OCD: Evaluating Augmentation Options

The network meta-analysis reveals that several augmentation agents, including memantine, risperidone, topiramate, lamotrigine, and aripiprazole, demonstrate significant efficacy in reducing OCD symptoms compared to placebo. This study highlights the potential of these agents for improving treatment outcomes in patients with treatment-resistant OCD, offering a broader range of therapeutic options. The findings also underscore the importance of considering individual patient factors and baseline symptom severity in selecting the most appropriate augmentation strategy.

Seeking Treatment for OCD: A Collaborative Journey

If you are struggling with OCD, particularly if treatment-resistant, consult a mental health professional. They can assess your individual needs, discuss potential treatment options, and guide you through the complexities of managing this challenging condition. Working collaboratively with your healthcare provider is crucial for finding effective treatment and improving your quality of life.

Dr. Camel's Conclusion

This study, like a desert caravan seeking a path through the complexities of OCD, explores the potential of augmentation agents to enhance treatment outcomes. The findings suggest that several agents, including memantine, risperidone, and others, may offer a path towards improved symptom relief, offering hope for individuals with treatment-resistant OCD.

Date :
  1. Date Completed 2019-04-22
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

30576763

DOI: Digital Object Identifier

10.1016/j.pnpbp.2018.12.009

SNS
PICO Info
in preparation
Languages

English

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