Real-World Outcomes of Talimogene Laherparepvec Therapy: A Multi-Institutional Experience.

Author: CollichioFrances, DelmanKeith A, JajjaMohammad Raheel, LouieRaphael J, LoweMichael, OllilaDavid W, PerezMatthew C, SarnaikAmod A, SunJames, ZagerJonathan S

Paper Details 
Original Abstract of the Article :
BACKGROUND: Talimogene laherparepvec (TVEC) is an FDA-approved oncolytic herpes virus used to treat unresectable stage IIIB to IV metastatic melanoma via intralesional injection. This study aims to characterize the efficacy TVEC in patients with unresectable stage IIIB to IV melanoma. METHODS: We p...See full text at original site
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引用元:
https://doi.org/10.1016/j.jamcollsurg.2018.12.027

データ提供:米国国立医学図書館(NLM)

Talimogene Laherparepvec Therapy: A Real-World Look at Melanoma Treatment

The battle against melanoma, a dangerous form of skin cancer, is a constant quest for effective treatment strategies. This study delved into the real-world effectiveness of talimogene laherparepvec (TVEC), an FDA-approved oncolytic virus therapy, in treating patients with unresectable melanoma. The authors analyzed data from a multi-institutional study, examining the clinical characteristics, treatment outcomes, and side effects of TVEC therapy. Their goal was to provide a comprehensive evaluation of this promising treatment approach in a real-world setting.

TVEC: A Potentially Durable Treatment Option

The study found that TVEC was well tolerated, with minimal side effects. It also demonstrated a significant complete local response in a substantial proportion of patients, suggesting that TVEC can be a durable treatment option for melanoma, particularly in advanced stages of the disease.

Hope for Patients with Unresectable Melanoma

This research offers valuable insights into the potential of TVEC as a treatment option for patients with unresectable melanoma. The study's findings suggest that TVEC can be a safe and effective therapy, providing hope for patients with limited treatment options and contributing to the ongoing search for new and innovative ways to combat this challenging disease.

Dr.Camel's Conclusion

This study underscores the importance of real-world research in evaluating new treatment approaches for complex diseases like melanoma. It's like finding a hidden spring in the desert—a valuable resource that can sustain life and provide hope for a brighter future.

Date :
  1. Date Completed 2020-03-16
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

30690076

DOI: Digital Object Identifier

10.1016/j.jamcollsurg.2018.12.027

SNS
PICO Info
in preparation
Languages

English

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