Paper Details

  1. Home
  2. Paper Details

Nephrotic Syndrome: Oedema Formation and Its Treatment With Diuretics.

Author: AshmanNeil, GuptaSanjana, PepperRuth J, WalshStephen B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article discusses the current paradigms of oedema in nephrosis, including emerging mechanisms like the role of the epithelial sodium channel in the collecting duct. The article also explores traditional and novel therapies for the treatment of nephrotic oedema, highlighting the need for further clinical trials to guide clinicians in the rational use of therapy.
Paper Details　
Original Abstract of the Article :
Oedema is a defining element of the nephrotic syndrome. Its' management varies considerably between clinicians, with no national or international clinical guidelines, and hence variable outcomes. Oedema may have serious sequelae such as immobility, skin breakdown and local or systemic infection. Tre...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341062/

データ提供：米国国立医学図書館（NLM）

Nephrotic Syndrome: Understanding and Managing Edema

The field of nephrology focuses on the diagnosis and treatment of kidney diseases. Nephrotic syndrome is a serious kidney disorder that can lead to edema, a condition characterized by fluid retention and swelling. This study delves into the mechanisms of edema formation in nephrotic syndrome and examines the current treatment paradigms for managing this symptom. Researchers highlight the role of the epithelial sodium channel in the collecting duct and discuss the physiological basis for traditional and novel therapies for nephrotic edema. Their analysis underscores the need for further research to develop more effective treatments for nephrotic edema.

Edema in Nephrotic Syndrome: A Complex Challenge

This research sheds light on the complexities of edema formation in nephrotic syndrome. The study emphasizes the importance of understanding the underlying mechanisms of edema and highlights the limitations of current treatment options. Further research is needed to develop more effective and targeted therapies for managing this symptom.

Living with Kidney Disease: A Journey of Self-Management and Support

Individuals with kidney disease often face a lifelong journey of self-management. It's important to work closely with a nephrologist to develop an individualized treatment plan and to access support services that can help manage the challenges of living with kidney disease.

Dr. Camel's Conclusion

This study is like a map of the kidney, revealing the intricate mechanisms that contribute to edema in nephrotic syndrome. The research underscores the need for a better understanding of this complex condition and highlights the importance of ongoing research to develop more effective treatments.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

30697163

DOI: Digital Object Identifier

PMC6341062

Related Literature

Article Analysis
・Side Effects of amiloride
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.