[Necrotic leg ulcers after topical application of chlormethine].

Author: AsgariR, BagotM, GaryC, GautierV, LazarethI, PriolletP

Paper Details 
Original Abstract of the Article :
BACKGROUND: Topical chlormethine has been widely used in the early stages of mycosis fungoides for many years. Cutaneous reactions (skin irritation and itch) are the most frequent adverse effects. Herein we report a rare side effect: severe necrotic leg ulcers. PATIENTS AND METHODS: An 82-year-old ...See full text at original site
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引用元:
https://doi.org/10.1016/j.annder.2018.12.001

データ提供:米国国立医学図書館(NLM)

A Rare Side Effect: Necrotic Leg Ulcers Following Topical Chlormethine Application

Topical chlormethine, a medication commonly used for the treatment of mycosis fungoides, is generally considered safe, with common side effects such as skin irritation and itching. However, this case report, like a curious traveler stumbling upon an unexpected oasis, describes a rare and serious side effect of topical chlormethine: necrotic leg ulcers. The report details the case of an 82-year-old woman who developed severe necrotic ulcers on her lower limbs after using topical chlormethine.

The case report suggests a possible link between topical chlormethine and the development of necrotic leg ulcers, but further investigation is needed to confirm this association. The report serves as a reminder that even commonly used medications can have rare and serious side effects, highlighting the importance of careful monitoring and prompt intervention in cases of adverse events.

A Rare but Serious Side Effect: Necrotic Leg Ulcers and Topical Chlormethine

This case report highlights a rare but serious side effect of topical chlormethine. While this side effect is uncommon, it underscores the importance of careful monitoring and prompt intervention in cases of adverse events. This report serves as a reminder that even seemingly safe medications can have unexpected consequences, emphasizing the need for vigilant observation and early recognition of potential problems.

Health Implications and Potential Applications

This case report highlights the importance of thorough patient monitoring and prompt intervention in cases of adverse events associated with medication use. The findings emphasize the need for continued research and surveillance to identify rare side effects and ensure the safe and effective use of medications. The report serves as a reminder that even seemingly safe medications can have unexpected consequences, reinforcing the need for vigilance and careful monitoring in clinical practice.

Dr. Camel's Conclusion

This case report is a reminder that the desert of medical knowledge is vast and full of surprises. Even seemingly familiar pathways can lead to unexpected destinations. We must remain vigilant, constantly seeking new information and adapting our approaches to ensure the safety and well-being of our patients.

Date :
  1. Date Completed 2019-12-12
  2. Date Revised 2019-12-17
Further Info :

Pubmed ID

30704945

DOI: Digital Object Identifier

10.1016/j.annder.2018.12.001

Related Literature

SNS
PICO Info
in preparation
Languages

French

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