Procalcitonin, mid-regional proadrenomedullin and C-reactive protein in predicting treatment outcome in community-acquired febrile urinary tract infection.

Author: AblijHans Christiaan, DelfosNathalie Manon, KosterTed, LeytenEliane Madeleine Sophie, StalenhoefJanneke Evelyne, WilsonDarius Cameron, van 't WoutJohannes Jan Willem, van DisselJaap Tamino, van NieuwkoopCees, van der ReijdenTanny J K, van der StarreWillize Elizabeth

Paper Details 
Original Abstract of the Article :
A reduction in duration of antibiotic therapy is crucial in minimizing the development of antimicrobial resistance, drug-related side effects and health care costs. The minimal effective duration of antimicrobial therapy for febrile urinary tract infections (fUTI) remains a topic of uncertainty, esp...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376649/

データ提供:米国国立医学図書館(NLM)

Febrile Urinary Tract Infection: A Desert Storm in the Body

Urinary tract infections (UTIs), a common and often painful condition, are like desert storms, disrupting the body's delicate balance. This study, like a team of researchers seeking to navigate the intricacies of infection management, investigates the use of biomarkers, like guiding beacons, to optimize antibiotic treatment for febrile UTIs, infections accompanied by fever. The study focuses on three key biomarkers—procalcitonin, mid-regional proadrenomedullin, and C-reactive protein—examining their predictive value for treatment outcomes.

Biomarkers: A New Map in the Desert of Infection Management

The study's findings, like a well-defined map leading to a safe passage, suggest that these biomarkers can provide valuable information for guiding antibiotic treatment decisions for febrile UTIs. By monitoring changes in biomarker levels, clinicians can potentially shorten the duration of antibiotic therapy, minimizing the risk of antibiotic resistance and side effects, while ensuring optimal patient outcomes.

Navigating the Desert of Infection: A More Precise Approach

This research, like a seasoned traveler with a keen understanding of the desert landscape, offers a more precise and individualized approach to managing febrile UTIs. The findings highlight the potential of biomarkers to guide antibiotic treatment decisions, potentially leading to shorter treatment durations, improved outcomes, and reduced side effects. This is a significant step towards more efficient and effective infection management.

Dr. Camel's Conclusion

This study, like a well-equipped caravan navigating a challenging terrain, emphasizes the importance of personalized medicine in infection management. The findings suggest that biomarkers can be valuable tools for optimizing antibiotic therapy, leading to better patient outcomes and potentially reducing the emergence of antibiotic resistance.

Date :
  1. Date Completed 2019-04-01
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

30764769

DOI: Digital Object Identifier

PMC6376649

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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