Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer.

Author: GaoYanfeng, HuoXiongwei, LiHan John, PangLizhi, QianSteven Y, YangJuechen, ZhouShuang

Paper Details 
Original Abstract of the Article :
The thunder god vine (Tripterygium wilfordii Hook. F) is traditionally used for inflammation-related diseases in traditional Chinese medicine. In recent years, celastrol (a natural compound from the root of the thunder god vine) has attracted great interest for its potential anticancer activities. T...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30773944

データ提供:米国国立医学図書館(NLM)

Celastrol: A Potential Weapon Against Colorectal Cancer

Colorectal cancer, like a relentless sandstorm, poses a significant threat to human health. This study investigates the potential of celastrol, a natural compound, as a weapon against this formidable foe.

Celastrol Inhibits Colorectal Cancer Growth and Angiogenesis

The researchers discovered that celastrol effectively inhibited the growth and migration of colorectal cancer cells. They also found that celastrol suppressed the activity of nitric oxide synthase (NOS), a key enzyme involved in tumor angiogenesis. These findings suggest that celastrol may offer a promising strategy for fighting colorectal cancer.

A New Oasis in the Desert of Colorectal Cancer Treatment

This research sheds light on the potential of celastrol as a novel treatment option for colorectal cancer. Its ability to target multiple aspects of tumor growth, including angiogenesis, makes it a valuable tool in the fight against this devastating disease.

Dr.Camel's Conclusion

This study is a refreshing oasis in the desert of colorectal cancer research. Celastrol, with its ability to inhibit tumor growth and angiogenesis, holds great promise as a new weapon against this disease. This research underscores the importance of exploring natural compounds for their potential medicinal properties, offering hope for a brighter future in the fight against cancer.

Date :
  1. Date Completed 2019-09-06
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

30773944

DOI: Digital Object Identifier

NIHMS1042175

Related Literature

SNS
PICO Info
in preparation
Languages

English

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