Uterine fibroids: an update on current and emerging medical treatment options.

Author: BastianelliCarlo, BenagianoGiuseppe, BrosensIvo, FarrisManuela, RosatoElena

Paper Details 
Original Abstract of the Article :
Uterine fibroids are the most common gynecological disorder, classically requiring surgery when symptomatic. Although attempts at finding a nonsurgical cure date back to centuries, it is only around the middle of the last century that serious attempts at a medical treatment were carried out. Initial...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350833/

データ提供:米国国立医学図書館(NLM)

Uterine Fibroids: Exploring New Horizons in Treatment

Uterine fibroids, a common gynecological disorder, can cause a range of symptoms, often requiring surgical intervention. While surgical approaches have been the mainstay of treatment, medical therapies have gained increasing attention in recent years. This review delves into the history and evolution of medical treatment for uterine fibroids, exploring the use of progestins, estrogen-progestin combinations, gonadotropin-releasing hormone (GnRH) analogs, and selective progesterone receptor modulators.

New Hope for Medical Treatment

The authors highlight the progress made in developing effective medical therapies for uterine fibroids. The introduction of GnRH analogs, particularly antagonists like cetrorelix, has brought about significant improvements, offering a viable alternative to surgery in certain cases. The emergence of non-peptidic, orally active GnRH-receptor blockers like Elagolix and the use of selective progesterone receptor modulators like Mifepristone and Ulipristal acetate have further expanded the treatment options. While some caution is needed regarding potential liver complications with Ulipristal acetate, these new therapies hold promise for long-term medical management of uterine fibroids, especially in premenopausal women.

Navigating the Landscape of Uterine Fibroid Treatment

This review provides valuable insights into the evolving landscape of uterine fibroid treatment. Like a camel traversing a vast desert, we must explore all available paths to find the most effective solutions for patients. The advancements in medical therapies, combined with ongoing research, offer hope for a future where uterine fibroids can be managed effectively, minimizing the need for invasive interventions.

Dr.Camel's Conclusion

Uterine fibroids, like a sandstorm in the desert, can disrupt a woman's life. But thanks to the advancements in medical treatment, we are better equipped to combat this condition. The development of new therapies, like finding a hidden oasis in the desert, offers hope and possibilities for a brighter future for women facing uterine fibroids.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

30774352

DOI: Digital Object Identifier

PMC6350833

SNS
PICO Info
in preparation
Languages

English

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