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Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT.

Author: BarnesThomas Re, BoweSamantha, BuckDeborah, ByrneRory, DaviesLinda, DudleyRobert, FrenchPaul, GriffithsHelen, GumleyAndrew, HudsonJemma, HuttonPaul, KingdonDavid, MacLennanGraeme, McLeodHamish J, MorrisonAnthony P, NorrieJohn, PyleMelissa, SchwannauerMatthias, ShieldsGemma, SyrettSuzy, TullySarah, TurkingtonDouglas

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

There is limited evidence regarding the effectiveness of pharmacological or psychological interventions for clozapine-resistant schizophrenia (CRS), a condition that occurs in patients with inadequate response to clozapine.
Paper Details　
Original Abstract of the Article :
Clozapine (clozaril, Mylan Products Ltd) is a first-choice treatment for people with schizophrenia who have a poor response to standard antipsychotic medication. However, a significant number of patients who trial clozapine have an inadequate response and experience persistent symptoms, called cloza...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409493/

データ提供：米国国立医学図書館（NLM）

Cognitive-Behavioral Therapy for Clozapine-Resistant Schizophrenia: A Camel's Journey Through the Mind

This research explores the challenges of treating clozapine-resistant schizophrenia, a condition that often leaves patients struggling with persistent symptoms despite treatment with standard antipsychotic medications. The study aimed to investigate the effectiveness of cognitive-behavioral therapy (CBT) as a potential intervention for this challenging patient population. The authors sought to shed light on the role of CBT in improving the lives of individuals with clozapine-resistant schizophrenia.

CBT: A Guiding Compass in the Desert of Schizophrenia

The study aimed to evaluate the effectiveness of CBT for clozapine-resistant schizophrenia, a condition that poses significant challenges to both patients and clinicians. The authors recognized the lack of evidence surrounding the use of psychological interventions for this population, highlighting the need for further research in this area. CBT, in its essence, provides individuals with tools to manage their thoughts, feelings, and behaviors, offering a potential pathway toward improved mental well-being.

The Camel's Take: Unlocking Potential

This research emphasizes the potential of CBT as a complementary therapy for patients with clozapine-resistant schizophrenia. By addressing the cognitive and behavioral aspects of the condition, CBT may help individuals gain a greater sense of control over their symptoms and improve their overall quality of life. Think of it as a guiding compass in a vast desert, helping individuals navigate the challenging terrain of mental illness.

Dr.Camel's Conclusion

This study encourages further exploration of CBT as a promising intervention for clozapine-resistant schizophrenia. By addressing the cognitive and behavioral aspects of the condition, CBT holds potential for improving mental health and well-being, offering a glimmer of hope for patients and clinicians navigating the complex landscape of mental illness.

Date :
  1. Date Completed 2020-06-04
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

30806619

DOI: Digital Object Identifier

PMC6409493

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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