Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production.

Author: KayserOliver, Kohnen-JohannsenKathrin Laura

Paper Details 
Original Abstract of the Article :
Tropane alkaloids (TA) are valuable secondary plant metabolites which are mostly found in high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are characterized by their unique bicyclic tropane ring system, can be divided into three major groups: hyoscyamine and scopola...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412926/

データ提供:米国国立医学図書館(NLM)

Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production

Tropane alkaloids, a diverse group of naturally occurring compounds found in plants like deadly nightshade and coca, are a fascinating field of study. This review provides a comprehensive overview of their chemistry, pharmacology, biosynthesis, and production. It explores the various uses of these compounds, ranging from legitimate medical applications to the infamous illicit drug cocaine.

From Ancient Remedies to Modern Medicine: The Evolution of Tropane Alkaloids

The authors highlight the historical significance of tropane alkaloids, tracing their use in traditional medicine back centuries. They then delve into their modern applications, such as the use of scopolamine to treat nausea and motion sickness. The review also discusses the complex biosynthesis of these compounds in plants, exploring the potential for using tissue culture and microbial biosynthesis to produce them more efficiently.

Understanding the Potential and Risks: A Balanced Perspective

While tropane alkaloids have valuable therapeutic properties, it's crucial to understand their potential risks. As a camel who's traversed many deserts, I know the importance of staying hydrated! The review reminds us of the dangers of cocaine, emphasizing the need for responsible use and proper regulation. This balanced perspective helps us appreciate the multifaceted nature of these compounds and their impact on human health.

Dr. Camel's Conclusion

This review takes us on a journey through the fascinating world of tropane alkaloids, from ancient remedies to modern medicine. From the bustling marketplace of natural products to the clandestine world of illicit drugs, these compounds have played a significant role in human history. The authors meticulously explore the various facets of these compounds, providing valuable insights into their chemistry, pharmacology, and production. It's a reminder that even the most fascinating discoveries require careful consideration of both potential benefits and risks.

Date :
  1. Date Completed 2019-06-12
  2. Date Revised 2023-10-06
Further Info :

Pubmed ID

30813289

DOI: Digital Object Identifier

PMC6412926

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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