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Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production.
Author: KayserOliver, Kohnen-JohannsenKathrin Laura
Original Abstract of the Article :
Tropane alkaloids (TA) are valuable secondary plant metabolites which are mostly found in high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are characterized by their unique bicyclic tropane ring system, can be divided into three major groups: hyoscyamine and scopola...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412926/
データ提供:米国国立医学図書館(NLM)
Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production
Tropane alkaloids, a diverse group of naturally occurring compounds found in plants like deadly nightshade and coca, are a fascinating field of study. This review provides a comprehensive overview of their chemistry, pharmacology, biosynthesis, and production. It explores the various uses of these compounds, ranging from legitimate medical applications to the infamous illicit drug cocaine.
From Ancient Remedies to Modern Medicine: The Evolution of Tropane Alkaloids
The authors highlight the historical significance of tropane alkaloids, tracing their use in traditional medicine back centuries. They then delve into their modern applications, such as the use of scopolamine to treat nausea and motion sickness. The review also discusses the complex biosynthesis of these compounds in plants, exploring the potential for using tissue culture and microbial biosynthesis to produce them more efficiently.
Understanding the Potential and Risks: A Balanced Perspective
While tropane alkaloids have valuable therapeutic properties, it's crucial to understand their potential risks. As a camel who's traversed many deserts, I know the importance of staying hydrated! The review reminds us of the dangers of cocaine, emphasizing the need for responsible use and proper regulation. This balanced perspective helps us appreciate the multifaceted nature of these compounds and their impact on human health.
Dr. Camel's Conclusion
This review takes us on a journey through the fascinating world of tropane alkaloids, from ancient remedies to modern medicine. From the bustling marketplace of natural products to the clandestine world of illicit drugs, these compounds have played a significant role in human history. The authors meticulously explore the various facets of these compounds, providing valuable insights into their chemistry, pharmacology, and production. It's a reminder that even the most fascinating discoveries require careful consideration of both potential benefits and risks.
Date :
- Date Completed 2019-06-12
- Date Revised 2023-10-06
Further Info :
Related Literature
English
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