Treatment of Dactylitis and Enthesitis in Psoriatic Arthritis with Biologic Agents: A Systematic Review and Metaanalysis.

Author: GniadeckiRobert, MouradAhmed

Paper Details 
Original Abstract of the Article :
Biologic agents with different mechanisms of action [inhibitors of tumor necrosis factor-α (TNF-α), interleukin (IL)-12/23, and IL-17] showed efficacy in randomized controlled trials (RCT) in the treatment of psoriatic arthritis. We conducted a pooled metaanalysis of these agents for treatment of da...See full text at original site
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引用元:
https://doi.org/10.3899/jrheum.180797

データ提供:米国国立医学図書館(NLM)

Biologic Agents: A New Oasis for Psoriatic Arthritis

Psoriatic arthritis, a chronic inflammatory condition that affects the joints and skin, can be likened to a persistent desert sandstorm, causing pain, inflammation, and stiffness. This research explores the effectiveness of biologic agents, a class of drugs that target specific components of the immune system, in treating dactylitis (inflammation of the fingers and toes) and enthesitis (inflammation of the tendons and ligaments) in patients with psoriatic arthritis. The authors reviewed and analyzed data from multiple clinical trials, seeking to assess the impact of these medications on various aspects of psoriatic arthritis. It's like a group of camels carefully evaluating different oases in the desert, seeking the most effective remedies for this debilitating condition.

Biologic Agents: A Promising Path for Psoriatic Arthritis Treatment

The study reveals that biologic agents demonstrate significant efficacy in treating dactylitis and enthesitis in patients with psoriatic arthritis. The data suggests that these medications can help reduce inflammation, improve joint function, and improve overall quality of life.

Finding Relief: Navigating the Desert of Psoriatic Arthritis

This research provides hope for those living with psoriatic arthritis. By understanding the effectiveness of biologic agents, we can identify more effective treatments and help patients navigate the challenges of this chronic condition.

Dr. Camel's Conclusion

This research highlights the potential of biologic agents to alleviate the symptoms of psoriatic arthritis, offering a new oasis in the desert of chronic inflammation. By understanding the mechanisms of action and efficacy of these medications, we can potentially find better ways to manage this debilitating condition and improve the quality of life for patients.

Date :
  1. Date Completed 2021-05-20
  2. Date Revised 2021-05-20
Further Info :

Pubmed ID

30824641

DOI: Digital Object Identifier

10.3899/jrheum.180797

Related Literature

SNS
PICO Info
in preparation
Languages

English

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