Paper Details 
Original Abstract of the Article :
These studies were designed to investigate the effects of the chrysotherapeutic agents auranofin and myochrysine (GST) on hepatic and renal drug-metabolizing enzymes and heme metabolism. Male Sprague-Dawley rats were either administered a single dose of auranofin (17, 34, or 68 mg/kg, p.o.) or admin...See full text at original site
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引用元:
https://doi.org/10.1016/0006-2952(86)90386-2

データ提供:米国国立医学図書館(NLM)

Chrysotherapy: A Desert Oasis for Rheumatoid Arthritis

This research investigates the effects of chrysotherapy agents, gold-based medications used to treat rheumatoid arthritis (RA), on various metabolic processes in the liver and kidneys. The researchers explored the impact of auranofin and gold sodium thiomalate on drug metabolism, heme metabolism, and enzyme activity in rats. Imagine rheumatoid arthritis as a desert storm, wreaking havoc on the body's joints and causing pain and inflammation. The researchers sought to understand how these chrysotherapy agents might affect the body's internal ecosystem in response to this disease.

Navigating the Desert of Rheumatoid Arthritis: A Guide to Chrysotherapy

The study revealed that these chrysotherapy agents can influence certain metabolic pathways in the liver and kidneys, potentially affecting drug metabolism and heme metabolism. This is like observing the intricate balance of a desert ecosystem, where the introduction of new elements can have ripple effects on the entire system. The study highlights the importance of understanding the potential side effects of these medications and the need for careful monitoring during treatment.

Protecting the Oasis: A Guide to Responsible Use of Chrysotherapy

This research provides valuable insights into the mechanisms of action of chrysotherapy agents. It underscores the importance of carefully considering the potential benefits and risks of these medications, particularly in the context of individual patient needs and potential drug interactions. It's like being aware of the delicate balance of a desert ecosystem and using resources responsibly to ensure its sustainability.

Dr.Camel's Conclusion

This research contributes to our understanding of the complex interplay between chrysotherapy, metabolic processes, and the management of rheumatoid arthritis. It highlights the importance of personalized treatment approaches and the need for careful monitoring during chrysotherapy to ensure patient safety and optimize treatment outcomes. Remember, even in the vast desert of medical treatments, there are often intricate ecosystems that require careful navigation and understanding.

Date :
  1. Date Completed 1986-10-02
  2. Date Revised 2019-06-23
Further Info :

Pubmed ID

3092830

DOI: Digital Object Identifier

10.1016/0006-2952(86)90386-2

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English

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