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Comparative Study Between Topical Gatifloxacin 0.5% and Moxifloxacin 0.5% as a Prophylactic Measure Before Intraocular Surgery.

Author: Abdel-MeguidAsser Ahmed Ehsan, ElmenofyTarek Mohamed Ibrahim, GabrAhmed Fathy, NassefMohamed Abd El Hamid, SaidMohamed Mostafa

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Moxifloxacin 0.5% ophthalmic solution penetrated the anterior chamber more effectively than gatifloxacin 0.5% in 100 patients undergoing eye surgery. Moxifloxacin was more effective for intraocular surgery prophylaxis, while gatifloxacin was more effective for reducing conjunctival bacterial load before extraocular and refractive surgeries.
Paper Details　
Original Abstract of the Article :
<b><i>Purpose:</i></b> To compare equal concentrations (0.5%) of moxifloxacin and gatifloxacin ophthalmic solutions with regard to conjunctival bacterial reduction as well as anterior chamber penetration. <b><i>Methods:</i></b> One hundred patients were divided into 2 groups. Group A received moxif...See full text at original site
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引用元：
https://doi.org/10.1089/jop.2018.0088

データ提供：米国国立医学図書館（NLM）

Preventing Infection Before Eye Surgery: Moxifloxacin vs. Gatifloxacin

Eye surgeries require strict infection control measures. This study compared the effectiveness of moxifloxacin and gatifloxacin ophthalmic solutions in reducing conjunctival bacteria and their penetration into the anterior chamber before intraocular surgery. The researchers conducted a study to determine the most effective prophylactic antibiotic for minimizing infection risk.

Moxifloxacin: A Superior Prophylactic Antibiotic for Intraocular Surgery

The study found that moxifloxacin had a significantly higher aqueous concentration compared to gatifloxacin, demonstrating its superior penetration into the anterior chamber. The results suggest that moxifloxacin may be the more effective prophylactic antibiotic for intraocular surgeries, reducing the risk of post-operative infection. The study highlights the importance of selecting the appropriate antibiotic based on its penetration capabilities for optimal infection prevention.

Protecting Your Eyes During Surgery: Choosing the Right Antibiotic

This research underscores the importance of choosing the right antibiotic for preventing infection during eye surgery. While both moxifloxacin and gatifloxacin showed effectiveness in reducing conjunctival bacteria, moxifloxacin demonstrated superior penetration into the anterior chamber, making it the preferred prophylactic antibiotic for intraocular surgeries. Remember, choosing the right antibiotic can significantly reduce the risk of infection and ensure a successful surgical outcome.

Dr. Camel's Conclusion

This comparative study provides valuable insights into the choice of prophylactic antibiotics for eye surgery. Moxifloxacin emerges as a more effective option for intraocular surgeries due to its superior penetration into the anterior chamber. Remember, protecting your eyes during surgery is crucial, and choosing the right antibiotic can significantly reduce the risk of infection and ensure a smooth recovery.

Date :
  1. Date Completed 2020-09-22
  2. Date Revised 2020-09-22
Further Info :

Pubmed ID

30950680

DOI: Digital Object Identifier

10.1089/jop.2018.0088

Related Literature

Article Analysis
・Effects of gatifloxacin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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