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Impact of gestrinone on the course of asymptomatic endometriosis.

Author: CookeI D, ThomasE J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effectiveness of gestrinone, a new drug, in treating endometriosis. The study found that gestrinone significantly prevented the worsening of endometriosis compared to placebo. While there was no statistically significant difference in the complete elimination of endometriosis, gestrinone was significantly better at improving the condition overall. The study concludes that gestrinone is an effective treatment for endometriosis and suggests that treatment is warranted for all patients, as at least 23% experience disease progression without treatment.
Paper Details　
Original Abstract of the Article :
A new drug, gestrinone, was subjected to the first double blind, randomised placebo controlled trial of any treatment of endometriosis. The disease deteriorated in eight (47%) of the 17 patients prescribed placebo (95% confidence limits 23% and 71%) compared with none of the 18 patients prescribed g...See full text at original site
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引用元：
https://doi.org/10.1136/bmj.294.6567.272

データ提供：米国国立医学図書館（NLM）

Gestrinone: A Promising Treatment for Endometriosis

Endometriosis, a condition where tissue similar to the uterine lining grows outside the uterus, can be a source of significant discomfort for women. This research investigates the effectiveness of gestrinone, a new drug, in treating asymptomatic endometriosis. The researchers conducted a double-blind, randomized, placebo-controlled trial to evaluate the impact of gestrinone on the progression of the disease.

Gestrinone Shows Promise in Endometriosis Treatment

The study found that gestrinone significantly improved the condition of endometriosis in patients, with a statistically significant difference in improvement compared to the placebo group. The results suggest that gestrinone could be a valuable treatment option for endometriosis, potentially offering relief from symptoms and preventing further deterioration of the disease.

Understanding and Managing Endometriosis

This study provides valuable insights into the potential of gestrinone as a treatment for endometriosis. The results highlight the importance of early diagnosis and intervention, especially considering that endometriosis can deteriorate in a significant proportion of patients. This knowledge can empower individuals to seek medical attention and explore treatment options if they suspect they may have endometriosis.

Dr. Camel's Conclusion

Like a camel traversing a rocky terrain, the path to managing endometriosis can be challenging. This study offers a glimmer of hope, showcasing the potential of gestrinone as a valuable treatment option. The research emphasizes the importance of early detection and timely intervention to potentially mitigate the progression of the disease. By understanding the complexities of endometriosis and exploring various treatment approaches, we can help individuals navigate this condition and find relief from its symptoms.

Date :
  1. Date Completed 1987-04-08
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

3101839

DOI: Digital Object Identifier

10.1136/bmj.294.6567.272

Related Literature

Article Analysis
・Effective treatment of endometriosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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