Paper Details 
Original Abstract of the Article :
An in vivo study was carried out to investigate the ultrastructural effects of triclabendazole (TCBZ) on immature Fasciola gigantica in a goat model. Five goats were infected with an oral gavage of 150 metacercarial cysts of F. gigantica and anthelmintic treatment occurred at 4 weeks post infection ...See full text at original site
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引用元:
https://doi.org/10.1016/j.actatropica.2019.04.015

データ提供:米国国立医学図書館(NLM)

Triclabendazole: A Powerful Weapon Against the Desert Fluke

The world of parasites is a vast and often unseen desert, with many organisms lurking beneath the surface. Fasciola gigantica, a parasitic fluke that infects livestock and humans, is a major concern for animal health and human well-being. This research explores the effects of triclabendazole (TCBZ), an anthelmintic drug, on immature Fasciola gigantica, investigating its potential to combat this debilitating parasite.

Destroying the Enemy: Triclabendazole and Fasciola gigantica

This research demonstrates the effectiveness of TCBZ in combating Fasciola gigantica. The study found that TCBZ caused significant damage to the parasite's tegument and internal tissues, effectively eliminating the parasite and preventing its further development. This finding highlights the potential of TCBZ as a powerful weapon against this devastating parasite, offering hope for improved animal health and human well-being.

A Journey Through the Desert: Understanding the Impact of TCBZ

This research provides valuable insights into the impact of TCBZ on Fasciola gigantica. The study meticulously documented the time-dependent ultrastructural changes caused by TCBZ, offering a detailed understanding of the drug's mechanism of action. This research is a testament to the ongoing quest to understand and combat parasitic infections, much like a caravan of explorers traversing a vast desert, seeking knowledge and solutions to overcome the challenges of the unknown.

Dr.Camel's Conclusion

This research is a beacon of hope in the fight against parasitic infections, highlighting the potential of TCBZ as a powerful weapon against Fasciola gigantica. It underscores the importance of understanding the intricate mechanisms of parasitic infections and developing effective treatments to protect both animal and human health. This research is a reminder that even in the most challenging deserts, there is always the possibility of finding a cure.

Date :
  1. Date Completed 2019-10-29
  2. Date Revised 2019-10-29
Further Info :

Pubmed ID

31028722

DOI: Digital Object Identifier

10.1016/j.actatropica.2019.04.015

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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