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Effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 infection.
Author: BadanesZachary I, JuddBonnie E, LedbetterEric C, MohammedHussni O, PenningtonMatthew R, SpertusChloe B, Van de WalleGerlinde R
Original Abstract of the Article :
OBJECTIVE: To determine the effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 (FHV-1) infection. ANIMALS: 14 healthy 6-month-old unvaccinated specific pathogen-free cats. PROCEDURES: On day 0, all cats were experimentally ino...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2460/ajvr.80.5.490
データ提供:米国国立医学図書館(NLM)
Raltegravir: A Potential Oasis in the Desert of Feline Herpesvirus-1 Infection
The feline world, like the vast desert, faces its own unique health challenges. Feline herpesvirus-1 (FHV-1) is a persistent threat, causing ocular and respiratory infections in cats. This study investigates the potential of raltegravir, an antiretroviral drug, as a treatment for FHV-1 infection in cats. The researchers conducted an experimental study to evaluate the effects of oral raltegravir on FHV-1-infected cats, exploring its impact on viral shedding, clinical signs, and immune responses.
Raltegravir Shows Promise: A Potential New Approach to FHV-1 Infection
The study revealed that cats treated with raltegravir exhibited shorter median durations of FHV-1 shedding and less severe signs of ocular and respiratory disease compared to those receiving a placebo. While the mean conjunctival FHV-1 titer and corneal epithelial leukocyte count did not show significant differences between the groups, the findings suggest that oral raltegravir may hold promise as a therapeutic option for FHV-1 infection in cats.
A Glimpse of Hope: Exploring Raltegravir's Potential in Feline Healthcare
This research, like a glimmer of hope in the desert, offers a potential new approach to the treatment of FHV-1 infection in cats. Further investigation into the efficacy and safety of raltegravir in cats is warranted to explore its potential for improving the health and well-being of feline companions.
Dr. Camel's Conclusion
This research is a testament to the ongoing search for innovative solutions in veterinary medicine. Like a skilled camel trader seeking new routes across the desert, researchers are constantly exploring new avenues for improving the health of our animal companions. The findings of this study offer a glimmer of hope for cats suffering from FHV-1 infection, paving the way for new therapeutic approaches and a brighter future for feline health.
Date :
- Date Completed 2019-06-20
- Date Revised 2019-06-20
Further Info :
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