Effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 infection.

Author: BadanesZachary I, JuddBonnie E, LedbetterEric C, MohammedHussni O, PenningtonMatthew R, SpertusChloe B, Van de WalleGerlinde R

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To determine the effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 (FHV-1) infection. ANIMALS: 14 healthy 6-month-old unvaccinated specific pathogen-free cats. PROCEDURES: On day 0, all cats were experimentally ino...See full text at original site
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引用元:
https://doi.org/10.2460/ajvr.80.5.490

データ提供:米国国立医学図書館(NLM)

Raltegravir: A Potential Oasis in the Desert of Feline Herpesvirus-1 Infection

The feline world, like the vast desert, faces its own unique health challenges. Feline herpesvirus-1 (FHV-1) is a persistent threat, causing ocular and respiratory infections in cats. This study investigates the potential of raltegravir, an antiretroviral drug, as a treatment for FHV-1 infection in cats. The researchers conducted an experimental study to evaluate the effects of oral raltegravir on FHV-1-infected cats, exploring its impact on viral shedding, clinical signs, and immune responses.

Raltegravir Shows Promise: A Potential New Approach to FHV-1 Infection

The study revealed that cats treated with raltegravir exhibited shorter median durations of FHV-1 shedding and less severe signs of ocular and respiratory disease compared to those receiving a placebo. While the mean conjunctival FHV-1 titer and corneal epithelial leukocyte count did not show significant differences between the groups, the findings suggest that oral raltegravir may hold promise as a therapeutic option for FHV-1 infection in cats.

A Glimpse of Hope: Exploring Raltegravir's Potential in Feline Healthcare

This research, like a glimmer of hope in the desert, offers a potential new approach to the treatment of FHV-1 infection in cats. Further investigation into the efficacy and safety of raltegravir in cats is warranted to explore its potential for improving the health and well-being of feline companions.

Dr. Camel's Conclusion

This research is a testament to the ongoing search for innovative solutions in veterinary medicine. Like a skilled camel trader seeking new routes across the desert, researchers are constantly exploring new avenues for improving the health of our animal companions. The findings of this study offer a glimmer of hope for cats suffering from FHV-1 infection, paving the way for new therapeutic approaches and a brighter future for feline health.

Date :
  1. Date Completed 2019-06-20
  2. Date Revised 2019-06-20
Further Info :

Pubmed ID

31034270

DOI: Digital Object Identifier

10.2460/ajvr.80.5.490

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SNS
PICO Info
in preparation
Languages

English

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