Paper Details
- Home
- Paper Details
Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo evaluation.
Author: BiradarMallanagouda S, BoppanaRashmi, DasKusal K, Krishna MohanG, KulkarniRaghavendra V, MutalikSrinivas, ReddyKakarla Raghava, SaBiswanath, Yadaorao RautSushil
Original Abstract of the Article :
In this report, novel pH-sensitive interpenetrated network (IPN) polyspheres were developed utilizing polyacrylamide-g-locust bean gum (PAAm-g-LBG) in combination with sodium alginate (SA) to achieve intestinal targeted delivery of ketoprofen. PAAm-g-LBG was synthesized under microwave irradiation w...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.colsurfb.2019.04.060
データ提供:米国国立医学図書館(NLM)
Targeted Delivery of Ketoprofen: A New Approach to Intestinal Health
This research explores a novel approach to targeted drug delivery, specifically focusing on the delivery of ketoprofen to the small intestine. The authors, like innovative engineers designing a precise delivery system, developed pH-sensitive polyspheres that release ketoprofen specifically in the small intestine. This innovative approach aims to maximize the therapeutic benefits of ketoprofen while minimizing its potential side effects.A Precise Delivery System
The research team meticulously designed and tested these pH-sensitive polyspheres, ensuring their ability to release ketoprofen at the desired location in the gastrointestinal tract. This precise delivery system, like a guided missile targeting a specific location, helps to maximize the drug's effectiveness while reducing unwanted side effects.Navigating the Desert of Drug Delivery
This research highlights the importance of developing targeted drug delivery systems to enhance the therapeutic efficacy and safety of medications. Like skilled desert navigators using precise instruments to find their way, researchers are constantly searching for new and innovative approaches to delivering drugs to their target sites. This study offers a promising example of how targeted drug delivery can improve patient outcomes and minimize unwanted side effects.Dr. Camel's Conclusion
This research explores a promising new approach to targeted drug delivery, offering a potential solution to the challenges of maximizing therapeutic benefits while minimizing side effects. It reminds us that the desert of drug delivery is constantly evolving, with researchers tirelessly seeking new ways to improve the safety and efficacy of medications.Date :
- Date Completed 2020-01-13
- Date Revised 2020-01-13
Further Info :
Related Literature
Article Analysis
SNS
PICO Info
in preparation
Languages
English
Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.