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Efficacy and Safety of Supportive Care Biosimilars Among Cancer Patients: A Systematic Review and Meta-Analysis.

Author: ChenYao, MaFei, ShiYanxia, ShiYehui, SunFeng, YanYusong, YangJichun, YangZhirong, YuShuqing, ZengHongmei, ZhangZilu

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This article discusses the growing use of biosimilars for supportive care in cancer treatment, particularly focusing on epoetin alfa, filgrastim, and pegfilgrastim. These biosimilars offer cost-effective alternatives to original biologics, potentially improving access to supportive care for cancer patients.
Paper Details　
Original Abstract of the Article :
Biologics are widely used to manage the side effects of cancer treatment (e.g., epoetin alfa is used to treat chemotherapy-induced anemia [CIA] and granulocyte colony-stimulating factors [G-CSFs] are used to treat chemotherapy-induced neutropenia [CIN]). As several patents for biologics used in canc...See full text at original site
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引用元：
https://doi.org/10.1007/s40259-019-00356-3

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Biosimilars in Cancer Treatment

The field of oncology is constantly evolving, with the development of new therapies and the refinement of existing ones. This systematic review and meta-analysis explores the efficacy and safety of supportive care biosimilars, a relatively new class of medications used to manage the side effects of cancer treatment. The researchers, like explorers mapping the vast desert of cancer therapy, conducted a comprehensive analysis of existing studies to evaluate the effectiveness of these biosimilars. This review offers a valuable overview of biosimilar medications, highlighting their potential to provide effective and affordable alternatives for cancer patients.

Efficacy and Safety of Supportive Care Biosimilars

The review found that supportive care biosimilars, such as epoetin alfa biosimilar and filgrastim biosimilar, demonstrated comparable efficacy and safety profiles to their originator biologics in managing chemotherapy-induced side effects. This suggests that biosimilars can provide a cost-effective alternative for cancer patients.

Implications for Cancer Care and Future Research

The review's findings underscore the growing importance of biosimilars in cancer care, offering a potentially more affordable approach to managing side effects. Future research should focus on the long-term impact of biosimilars, exploring their effectiveness in different patient populations and for various types of cancer.

Dr.Camel's Conclusion

This review serves as a guide through the vast desert of cancer treatment, highlighting the potential of biosimilars to provide effective and cost-effective solutions for patients. It encourages a more informed approach to selecting therapies, considering both efficacy and affordability in the pursuit of optimal cancer care.

Date :
  1. Date Completed 2019-12-25
  2. Date Revised 2019-12-25
Further Info :

Pubmed ID

31161461

DOI: Digital Object Identifier

10.1007/s40259-019-00356-3

Related Literature

Article Analysis
・Side Effects of epoetin alfa
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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