Fracture risk following intermission of osteoporosis therapy.

Author: , AbrahamsenB, BruyèreO, CooperC, DennisonE M, FerrariS, KanisJ A, McCloskeyE, Prieto-AlhambraD, SilvermanS

Paper Details 
Original Abstract of the Article :
Given the widespread practice of recommending drug holidays, we reviewed the impact of medication discontinuation of two common anti-osteoporosis therapies (bisphosphonates and denosumab). Trial evidence suggests the risk of new clinical fractures, and vertebral fracture increases when osteoporosis ...See full text at original site
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引用元:
https://doi.org/10.1007/s00198-019-05002-w

データ提供:米国国立医学図書館(NLM)

Fracture Risk: The Hidden Desert of Interrupted Osteoporosis Therapy

Osteoporosis, a condition characterized by weakened bones, is like a fragile sandcastle in the desert, vulnerable to collapse. This study, like a meticulous archaeologist examining the ruins of ancient civilizations, explores the potential consequences of interrupting osteoporosis treatment. It's a reminder that seemingly small actions can have significant repercussions, like a misplaced footstep leading to a tumble in the desert.

Interrupted Therapy: A Hidden Risk

The study found that stopping osteoporosis treatment with bisphosphonates or denosumab increased the risk of new fractures. This finding underscores the importance of maintaining consistent treatment, like diligently watering a desert oasis to prevent it from drying up.

Maintaining Bone Health: A Continuous Journey

This research suggests that maintaining bone health is an ongoing journey, not a temporary detour. It emphasizes the need for consistent treatment and close monitoring to prevent fractures and maintain bone strength, like a tireless camel caravan diligently navigating a long and arduous desert path.

Dr. Camel's Conclusion

This study, like a weathered stone in the desert, serves as a reminder of the enduring importance of long-term treatment adherence for osteoporosis. It highlights the need for careful consideration and thorough communication between patients and healthcare providers to ensure optimal bone health and prevent potential complications.
Date :
  1. Date Completed 2020-02-10
  2. Date Revised 2023-11-15
Further Info :

Pubmed ID

31175404

DOI: Digital Object Identifier

10.1007/s00198-019-05002-w

Related Literature

SNS
PICO Info
in preparation
Languages

English

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