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Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth.

Author: AxelssonInge, NaumburgEstelle, PrietschSílvio Om, ZhangLinjie

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This review suggests that the type of inhaled corticosteroid (ICS) and delivery device used to treat children with persistent asthma may impact their growth. Fluticasone at an equivalent dose appeared to have less of a suppressive effect on growth compared to beclomethasone and budesonide. Easyhaler may have less of an adverse effect on growth compared to Turbuhaler when used to deliver budesonide. However, the evidence from this review is not certain enough to inform the selection of ICS or delivery device for children with persistent asthma. Further research is needed.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Inhaled corticosteroids (ICS) are the most effective treatment for children with persistent asthma. Although treatment with ICS is generally considered to be safe in children, the potential adverse effects of these drugs on growth remains a matter of concern for parents and physicians. ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564081/

データ提供：米国国立医学図書館（NLM）

Inhaled Corticosteroids for Asthma: Finding the Right Path Through the Desert

The desert of [asthma] can be a challenging place to navigate, and finding the right treatment is crucial for ensuring a comfortable and healthy life. This study explores the impact of different [inhaled corticosteroids] and delivery devices on the growth of children with [asthma]. It’s like exploring different pathways through the desert, seeking the most effective and safe route to manage this complex condition. The study reviewed a series of [randomized controlled trials] that investigated the effects of different [inhaled corticosteroids] and delivery devices on the growth of children with [asthma]. The authors meticulously analyzed the findings, seeking to identify any potential differences in growth outcomes.

Fluticasone: A More Growth-Friendly Oasis

The study found that [fluticasone] may have a less suppressive effect on growth compared to other [inhaled corticosteroids] such as [beclomethasone] and [budesonide]. It’s like finding an oasis that promotes healthy growth and development, offering a more favorable environment for children with [asthma]. The study also suggests that the delivery device used for [inhaled corticosteroids] can influence growth outcomes. The authors found that [Easyhaler] may have a less adverse effect on growth compared to [Turbuhaler].

Navigating the Desert of Asthma: Finding the Right Path for Growth

This study emphasizes the importance of carefully considering the specific [inhaled corticosteroid] and delivery device when treating children with [asthma]. It’s like choosing the right path through the desert, ensuring that we provide the best possible care for our children while promoting healthy growth and development. Further research is needed to confirm these findings and identify the most effective and growth-friendly options for managing [asthma] in children.

Dr.Camel's Conclusion

This research highlights the potential impact of inhaled corticosteroids and delivery devices on growth in children with asthma. While fluticasone may be a more growth-friendly option, further research is needed to confirm these findings and guide treatment choices, ultimately leading us to a more effective and safe oasis for managing asthma in children.

Date :
  1. Date Completed 2020-02-07
  2. Date Revised 2023-01-06
Further Info :

Pubmed ID

31194879

DOI: Digital Object Identifier

PMC6564081

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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