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Pressurized IntraPeritoneal Aerosol Chemotherapy vs. intravenous chemotherapy for unresectable peritoneal metastases secondary to platinum resistant ovarian cancer - study protocol for a randomized control trial.
Author: AshwinK R, RauthanAmit, RohitKumar C, SomashekharS P
Original Abstract of the Article :
Despite optimal surgery and appropriate first-line chemotherapy, ∼70-80 % of patients with epithelial ovarian cancer will develop disease relapse. The prognosis is poor especially for women with Platinum resistant ovarian cancer. The standard treatment for these groups of patients is non-platinum-co...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545874/
データ提供:米国国立医学図書館(NLM)
Pressurized IntraPeritoneal Aerosol Chemotherapy: A Promising New Frontier in Ovarian Cancer Treatment
Ovarian cancer, a devastating disease, often presents with peritoneal metastases, even after optimal surgery and chemotherapy. This research explores the potential of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) as a novel and minimally invasive treatment option for unresectable peritoneal metastases secondary to platinum-resistant ovarian cancer. The authors highlight the limitations of conventional chemotherapy, including poor drug distribution and limited tissue penetration, which often hinder treatment effectiveness. PIPAC, a minimally invasive drug-delivery technique, aims to address these limitations by delivering chemotherapy directly into the peritoneal cavity as an aerosol under pressure. This innovative approach promises to enhance drug distribution and uptake within the peritoneal cavity, potentially improving treatment outcomes. This research outlines a randomized control trial designed to evaluate the efficacy and safety of PIPAC compared to intravenous chemotherapy in patients with platinum-resistant ovarian cancer.
PIPAC: A New Path Through the Desert of Ovarian Cancer Treatment
The potential of PIPAC as a treatment option for platinum-resistant ovarian cancer is incredibly exciting. It's like finding a hidden oasis in the vast desert of ovarian cancer treatment options, offering a new and potentially more effective approach. The randomized control trial will provide valuable data on its efficacy and safety compared to conventional chemotherapy, paving the way for a more targeted and less invasive treatment for this challenging disease.
The Promise of Targeted Therapies
This research highlights the importance of developing targeted therapies that address the specific needs of individual patients. It's like finding a hidden path through the vast desert of cancer treatment, leading us to more effective and less invasive approaches. This shift towards personalized and targeted therapies is crucial for improving outcomes and enhancing the quality of life for cancer patients.
Dr.Camel's Conclusion
PIPAC represents a promising new frontier in ovarian cancer treatment, offering a potential solution to the challenges posed by platinum-resistant disease. The ongoing research is a beacon of hope in the vast desert of ovarian cancer treatment, potentially leading to better outcomes and improved quality of life for patients.
Date :
- Date Completed n.d.
- Date Revised 2022-04-08
Further Info :
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