Paper Details

  1. Home
  2. Paper Details

[Efficacy and safety of neuroprotection in patients with primary open-angle glaucoma].

Author: AntipinaN A, BogdanovaD S, KlindyukT S, MalishevskayaT N, ShatskikhS V, YusupovA R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While high eye pressure is a major contributor to glaucoma, the disease can sometimes progress even when eye pressure is normal. This study emphasizes the need for new treatments that target other factors involved in glaucoma's progression, not just eye pressure.
Paper Details　
Original Abstract of the Article :
Elevated intraocular pressure (IOP) is considered one of the main factors in the development and progression of primary open-angle glaucoma (POAG). The main schemes of drug treatment and cell protection from glaucomatous damage are aimed particularly at reducing IOP. However, it is possible for the ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.17116/oftalma201913502183

データ提供：米国国立医学図書館（NLM）

Neuroprotection for Glaucoma

The field of [glaucoma] is constantly searching for better treatment options. This research focuses on the need for neuroprotective drugs to prevent further damage in patients with [primary open-angle glaucoma (POAG)]. It's like protecting the precious oases in the desert from encroaching sand dunes.

Beyond Intraocular Pressure

While lowering [intraocular pressure (IOP)] is a crucial part of managing POAG, this study highlights the need for drugs that target other factors contributing to disease progression. The research suggests that even with normalized IOP, POAG can continue to progress. This finding calls for a broader approach to treatment.

New Treatment Strategies for Glaucoma

This research emphasizes the importance of finding drugs that target the multiple mechanisms involved in POAG. By exploring neuroprotective options, we can potentially develop new treatments that slow down disease progression and preserve vision.

Dr.Camel's Conclusion

The desert of glaucoma can be a challenging place to navigate, but this research points to new strategies for treatment. By targeting not only IOP but also the underlying neurodegenerative processes, we can create a more effective shield against vision loss.

Date :
  1. Date Completed 2019-08-22
  2. Date Revised 2019-08-22
Further Info :

Pubmed ID

31215538

DOI: Digital Object Identifier

10.17116/oftalma201913502183

Related Literature

Article Analysis
・Effective treatment of glaucoma
SNS
PICO Info
in preparation
Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.