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Effects of Somatostatin Combined with Pantoprazole on Serum C-Reactive Protein and Intercellular Adhesion Molecule-1 in Severe Acute Pancreatitis.
Author: HuangLei, LiuJun, LiuYan, WangGuoliang, WangJun, XuXiangang
Original Abstract of the Article :
The objective of this study was to investigate effects of somatostatin combined with pantoprazole on serum C-reactive protein (CRP) and intercellular adhesion molecule-1 (ICAM-1) in severe acute pancreatitis (SAP) patients. It was an experimental study carried out from February 2016 to April 2018. E...See full text at original site
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引用元:
https://doi.org/10.29271/jcpsp.2019.07.683
データ提供:米国国立医学図書館(NLM)
Somatostatin and Pantoprazole: A Powerful Duo Against Severe Acute Pancreatitis
Severe acute pancreatitis, a serious inflammation of the pancreas, can be a challenging medical condition. This research delves into the potential benefits of combining somatostatin and pantoprazole in the treatment of severe acute pancreatitis. They conducted an experimental study with 82 patients, randomly assigning them to receive either pantoprazole alone or somatostatin combined with pantoprazole. They compared the effectiveness of the two treatment groups in terms of symptom relief, recovery time, and inflammation markers.
A Promising Combination
The study demonstrated that somatostatin combined with pantoprazole resulted in faster symptom relief, quicker recovery of intestinal function, and a shorter time on mechanical ventilation compared to pantoprazole alone. Additionally, the combined treatment led to lower levels of C-reactive protein (CRP) and intercellular adhesion molecule-1 (ICAM-1), suggesting a significant reduction in inflammation. This finding suggests that somatostatin combined with pantoprazole may be a more effective treatment for severe acute pancreatitis.
Managing Pancreatitis: A Collaborative Approach
The study highlights the potential benefits of using somatostatin in combination with pantoprazole for treating severe acute pancreatitis. The combination therapy may offer a more effective approach to managing inflammation and promoting faster recovery. Understanding the mechanisms of this combined treatment could lead to further refinements in the treatment of this serious condition. It is like a camel navigating a scorching desert, seeking shade and sustenance to survive the extreme conditions.
Dr.Camel's Conclusion
This research provides promising evidence for the effectiveness of somatostatin combined with pantoprazole in treating severe acute pancreatitis. The study demonstrates that this combination therapy can lead to faster recovery and reduced inflammation, offering a potential improvement in the management of this condition. This research encourages further investigation into the mechanisms of action and the long-term effects of this combined treatment.
Date :
- Date Completed 2020-01-24
- Date Revised 2020-01-24
Further Info :
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