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Effects of entecavir, tenofovir and telbivudine treatment on renal functions in chronic hepatitis B patients.
Author: AldemirM N, ArslanY, BayanK, KaraA V, OzcicekF, YıldırımY, ÇelenM K
Original Abstract of the Article :
BACKGROUND AND STUDY AIMS: The aim of this study was to enlighten the controversy about the renal safety of entecavir, tenofovir, and telbivudine treatments in chronic hepatitis B (CHB) patients by comparing these treatments in real-world conditions. PATIENTS AND METHODS: We retrospectively enrolle...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/31314188
データ提供:米国国立医学図書館(NLM)
Hepatitis B Treatment and Renal Function: A Desert Oasis of Care
Chronic hepatitis B (CHB) is a viral infection that affects the liver, posing a significant challenge to patient health. This study explores the effects of different antiviral medications on renal function in patients with CHB. The authors compare the impact of entecavir, tenofovir, and telbivudine on the estimated glomerular filtration rate (eGFR), a measure of kidney function.
Navigating the Terrain of Hepatitis B Treatment
This research highlights the complex relationship between antiviral medications used for CHB and renal function. Just as a desert traveler needs to choose their path carefully to avoid hazards, healthcare providers need to consider the potential impact of these medications on kidney health. The authors found that tenofovir was associated with a decrease in eGFR, while telbivudine was associated with an increase. Entecavir showed no significant effect on renal function.
Personalized Management for Hepatitis B
This study underscores the importance of personalized management for CHB patients, taking into account both treatment efficacy and potential side effects. Think of it as tailoring a journey to individual needs, choosing the best route and resources to ensure a successful outcome. By carefully considering individual factors, such as kidney function, we can provide the best possible care for CHB patients.
Dr. Camel's Conclusion
This study sheds light on the need for careful monitoring of renal function in patients with CHB treated with antiviral medications. Just as a camel needs a steady source of water to survive in the desert, patients with CHB require meticulous attention to their kidney health. By providing personalized care and monitoring for potential side effects, we can ensure a safe and effective journey to better health.
Date :
- Date Completed 2019-07-22
- Date Revised 2019-07-22
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