Symptom-specific effects of cognitive-behavioral therapy, sertraline, and their combination in a large randomized controlled trial of pediatric anxiety disorders.

Author: AlbanoAnne Marie, BirmaherBoris, CervinMatti, ComptonScott N, GoschElizabeth, KendallPhilip C, PiacentiniJohn, StorchEric A, WalkupJohn T

Paper Details 
Original Abstract of the Article :
BACKGROUND: Pediatric anxiety disorders are highly prevalent and associated with significant functional disabilities and lifelong morbidity. Cognitive-behavioral therapy (CBT), sertraline, and their combination are effective treatments, but little is known about how these treatments exert their effe...See full text at original site
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引用元:
https://doi.org/10.1111/jcpp.13124

データ提供:米国国立医学図書館(NLM)

Pediatric Anxiety: A Multi-faceted Approach

Anxiety disorders are a significant challenge for many children. This research dives into the complex world of pediatric anxiety disorders, investigating the effectiveness of cognitive-behavioral therapy (CBT), sertraline (an antidepressant), and a combination of both, in treating these disorders. This study is like a detailed map of the desert, revealing the intricate pathways of anxiety and its treatment. The researchers used a network intervention analysis (NIA), a sophisticated approach that allows them to map the connections between different symptoms of anxiety. This study recruited a large cohort of children with anxiety disorders, making it one of the largest randomized controlled trials on this topic. This extensive research effort is akin to a comprehensive desert expedition, providing valuable insights into the multifaceted nature of childhood anxiety.

Treatment Effects: Reducing Psychological Distress

The study found that all active treatments, CBT, sertraline, and the combination, showed positive effects in reducing various aspects of anxiety, particularly psychological distress, family interference, and avoidance. This finding is like finding a hidden oasis in the desert, providing relief from the scorching effects of anxiety. The researchers also discovered that psychological distress was the most central symptom in the disorder network, suggesting that interventions targeting this specific aspect of anxiety may be crucial for successful treatment.

Tailoring Treatment for Children with Anxiety

This research emphasizes the importance of considering the specific symptom domains targeted by interventions. It highlights the need for individualized treatment plans, taking into account the unique needs and challenges of each child. This is like finding the best camel for a specific desert journey, ensuring that the animal’s strengths and capabilities are aligned with the demands of the terrain.

Dr.Camel’s Conclusion

This research offers valuable insights into the treatment of pediatric anxiety disorders. By understanding the interconnectedness of different anxiety symptoms, researchers can develop more effective and personalized interventions. This is like learning to read the desert landscape, identifying the specific challenges and finding the best strategies for navigating the terrain.
Date :
  1. Date Completed 2021-09-15
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

31471911

DOI: Digital Object Identifier

10.1111/jcpp.13124

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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