Effective treatment of anxiety: A Synthesis of Findings from 89 Studies

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Original Abstract of the Article

Major Research Findings

There are a variety of treatments for anxiety disorders, including cognitive-behavioral therapy (CBT) and medication. Studies have shown that CBT is effective in improving the symptoms of anxiety disorders. Some medications can also help treat anxiety disorders.

For example, the study 12 showed that CBT improved the symptoms of anxiety disorders, and the effects were sustained over the long term. Furthermore, the study 72 showed that the combination of CBT and medication is more effective in improving the symptoms of anxiety disorders.

Also, the study 69 showed that it is important to use more intense exposures to enhance the effects of exposure therapy for phobias. This is because more intense exposures make it easier for patients to overcome their fear of phobias.

Treatment Summary

There are a variety of treatments for anxiety disorders, including cognitive-behavioral therapy (CBT) and medication. CBT is effective in improving the symptoms of anxiety disorders. Medication may be used to reduce the symptoms of anxiety disorders. Also, the effects of exposure therapy for phobias can be enhanced by using more intense exposures.

Benefits and Risks

Benefits Summary

Treatments for anxiety disorders offer a variety of benefits. For example, CBT has been shown to improve the symptoms of anxiety disorders, and the effects are sustained over the long term. Also, medication may be used to reduce the symptoms of anxiety disorders. Furthermore, the effects of exposure therapy for phobias can be enhanced by using more intense exposures.

Risks Summary

There are some risks associated with treatments for anxiety disorders. For example, medication can cause side effects. Also, using more intense exposures to enhance the effects of exposure therapy for phobias can be a difficult experience for patients.

Comparison Among Studies

Commonalities Among Studies

Many studies have shown that CBT is effective in improving the symptoms of anxiety disorders. Some medications can also help treat anxiety disorders.

Differences Among Studies

The effectiveness of certain treatments may vary across studies. For example, the study 69 showed that using more intense exposures could enhance the effects of exposure therapy for phobias, while other studies did not find this effect.

Consistency and Contradictions in Results

There are consistent findings in some studies of the effectiveness of treatments for anxiety disorders, but there are also contradictory findings in other studies. These inconsistencies may be due to differences in research methods, study participants, or other factors.

Notes on Application to Real Life

Treatments for anxiety disorders are not effective for all patients. There are also some risks associated with treatments. It is important to consult with a doctor or therapist before starting treatment.

Limitations of Current Research

There are many limitations to research on treatments for anxiety disorders. For example, many studies have small sample sizes, which may limit the generalizability of the findings. Also, many studies focus on a specific type of anxiety disorder and may not apply to other types of anxiety disorders.

Future Directions for Research

Further research is needed on treatments for anxiety disorders. In particular, studies involving different types of anxiety disorders and larger sample sizes are needed to develop effective treatments.

Conclusion

There are a variety of treatments for anxiety disorders. CBT is effective in improving the symptoms of anxiety disorders. Medication may be used to reduce the symptoms of anxiety disorders. Also, the effects of exposure therapy for phobias can be enhanced by using more intense exposures. Treatments for anxiety disorders are not effective for all patients. It is important to consult with a doctor or therapist before starting treatment.

Treatment List

Cognitive-behavioral therapy (CBT), Medication, Exposure therapy, Internet-based cognitive-behavioral therapy, Acceptance and commitment therapy (ACT), Guided imagery, Applied relaxation

Keywords
Benefit Keywords
Anxiety treatment
1
Anxiety treatment
2
Anxiety treatment
3
Reduced anxiety
4
Anxiety reduction
5
Anxiety reduction
6
Reduced anxiety
7
Anxiety relief
8
Reduced avoidance
Reduced panic
9
GAD treatment
10
Anxiety treatment
11
CBT for anxiety
12
Breathing and focused attention for anxiety
13
Placebo effect
14
Social anxiety disorder treatment
15
Treatment of depression and anxiety
16
Anxiety treatment
Depressive mood reduction
17
Anxiety treatment
Panic disorder treatment
18
Anxiety reduction
19
Anxiety reduction
Feasible primary care
20
Improved anxiety treatment
21
Improved social functions
Reduced symptoms
22
Pediatric anxiety treatment
23
CBT effective
24
Depression treatment
25
Reduced anxiety sensitivity
26
Medication for anxiety
28
Combined treatment social anxiety
29
Reduced anxiety symptoms
30
Anxiety management
31
CBT for GAD
32
Reduced anxiety
Reduced hypochondriasis
33
Improved pregnancy anxiety treatment
34
Effective treatment for anxiety disorders
35
Effective treatment for anxiety and depression
36
Anxiety treatment
37
Reduced alcohol use
Reduced anxiety
38
Anxiety treatment
39
Reduced anxiety symptoms
40
Depression treatment
41
Anxiety reduction
42
Media-delivered interventions
Self-help
43
Anxiety control
44
Reduced anxiety
45
Anxiety treatment
46
AS treatment
47
Telephone-delivered CBT
48
Improved depression remission
49
Anxiety treatment
50
Improved child anxiety
51
ACT-G for health anxiety
52
Cost effective treatment
Increased dissemination
Reduced anxiety
53
Anxiety relief
54
Treatment for anxiety disorders
55
Improved WM
56
Anxiety disorder treatment
Anxiety sensitivity reduction
57
Reduced GAD symptoms
Safe
58
ECT adherence
59
Reduced AS
60
Reduced anxiety
61
Anxiety disorder treatment
62
Anxiety reduction
Substance use reduction
63
GAD treatment
64
Reduced suicidal ideation
65
Improved MDD treatment
66
Anxiety treatment
67
Reduced anxiety
68
Improved tolerance
Reduced fear
69
Anxiety disorders treatment
Art therapy
70
Child anxiety reduction
Maternal anxiety reduction
71
Reduced anxiety symptoms
72
Improved side effects
Reduced anxiety
Reduced depression
73
Reduced anxiety
Reduced depression
74
Improved GAD outcome
75
Health anxiety treatment
Increased access to care
76
Improved anxiety treatment
77
Anxiety treatment
78
Medication for anxiety
Psychotherapy for anxiety
80
Anxiety reduction
Faster treatment
81
Reduced pregnancy anxiety
82
Behavioral strategies for dental anxiety
84
CBT treatment for pediatric anxiety
85
MBSR for anxiety
86
Anxiety reduction
87
Improved dental access
Reduced anxiety
88
Reduced anxiety symptom severity
89
Risk Keywords
Drowsiness
1
Drowsiness
2
Cardiovascular effects
4
Discontinuation rate
10
Abuse potential
Sedation
Withdrawal symptoms
18
Dropout
19
Anxiety
21
Anxiety exacerbation
25
Pain interference
27
Side effects
31
Treatment limitations
32
Anxiety disorders
43
High non-response rate
46
Anxiety sensitivity
48
Anxiety symptoms impact prognosis
49
Benzodiazepine risks
Lack of studies
50
None mentioned
51
None mentioned
57
Did not significantly reduce relapse rate
Limited sample size
58
ECT anxiety
59
Unresponsive patients
64
None
73
None reported
76
Nausea
79
Course of anxiety disorders
83
Pharmacological intervention side effects
84
Adverse effects
88
Literature analysis of 89 papers
Positive Content
86
Neutral Content
2
Negative Content
1
Article Type
62
18
22
20
89
1.

A test of the concept of "underlying depressive illness" in the treatment of anxiety states.

Author: WalshM R, DunckleyH G, SinclairJ M, SchiffA A

Anxiety treatment
Drowsiness

In a double-blind study of 4 weeks, fluphenazine with nortriptyline, an anxiolytic/antidepressant, showed greater improvement in anxiety and tension states than lorazepam, a pure anxiolytic. This suggests that a depressive element may be present in many patients with anxiety, requiring both anxiolytic and antidepressant treatment.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

2.

Anxiety states in family practice: an evaluation of the need for antidepressant as well as anxiolytic therapy.

Author: McGhieR L, O'HaraH, O'HaraJ, BrodieN H, DunckleyH G, SchiffA A

Anxiety treatment
Drowsiness

Fluphenazine/nortriptyline, an antidepressant/anxiolytic combination, showed greater improvement in anxiety symptoms compared to clorazepate, a pure anxiolytic, in patients with anxiety. This suggests a depressive component in many anxiety states.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

3.

Self help programme for anxiety in general practice: controlled trial of an anxiety management booklet.

Author: SorbyN G, ReavleyW, HuberJ W

Anxiety treatment

This study evaluated the effectiveness of an anxiety management booklet in addition to usual care for patients with panic disorder or generalized anxiety disorder. The booklet led to significant and rapid reductions in anxiety within the first two weeks, compared to a control group. Patients found the booklet easy to use and helpful. This study suggests that incorporating a simple, low-cost anxiety management booklet into general practice could significantly improve outcomes for patients with anxiety.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

4.

Propranolol and atenolol in the treatment of anxiety.

Author: PeetM, AliS

Reduced anxiety
Cardiovascular effects

Patients with generalized anxiety who have not responded to psychological treatment from their family doctor may require symptomatic drug treatment whilst awaiting specialist therapy. This study indicates that propranolol is effective and relatively safe for this purpose. Atenolol is also effective but has unacceptable cardiovascular effects in anxious patients.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Anxiety management training for anxiety states: positive compared with negative self-statements.

Author: RammE, MarksI M, YukselS, SternR S

Anxiety reduction

This study of 12 patients with chronic free-floating anxiety found that both positive and negative self-statement anxiety-management training were effective in reducing anxiety symptoms. There was a slight trend favoring positive self-instruction, particularly at follow-up.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms.

Author: SheehanD V, BallengerJ, JacobsenG

Anxiety reduction

This study of 57 patients with endogenous anxiety found that both imipramine hydrochloride and pheneizine sulfate were significantly more effective than placebo in reducing anxiety symptoms. Pheneizine tended to be more effective than imipramine, particularly in improving work and social function.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

7.

Efficacy of applied relaxation and cognitive-behavioral therapy in the treatment of generalized anxiety disorder.

Author: BorkovecT D, CostelloE

Reduced anxiety

This study of patients with generalized anxiety disorder (GAD) found that both applied relaxation (AR) and cognitive behavioral (CBT) therapies were more effective than nondirective (ND) therapy in reducing anxiety symptoms.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

8.

The effects of common and specific factors in short-term anxiety-provoking psychotherapy: a pilot process-outcome study.

Author: SvartbergM, SeltzerM H, StilesT C

Anxiety relief

This study compared the effectiveness of short-term anxiety-provoking psychotherapy (STAPP) to nondirective therapy. Both treatments were equally effective in reducing symptoms, suggesting that the therapeutic alliance, rather than specific techniques, is the primary driver of success.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

9.

[Conflict-centered individual therapy or integration of psychotherapy methods. Process of change in client-centered psychotherapy with and without behavioral exposure therapy in agoraphobia with panic disorder].

Author: TeuschL, BöhmeH, FinkeJ

Reduced avoidance
Reduced panic

This study compared the effects of two therapies for agoraphobia and panic: client-centered therapy (CCT) alone and CCT combined with behavioral exposure. Both therapies effectively reduced panic and avoidance behaviors. CCT alone promoted greater feelings of independence and less reliance on others, while the combined therapy helped patients feel more accepted by others. The study suggests that different therapies may work through different mechanisms and that combining therapies may enhance treatment outcomes.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : German

10.

Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: twenty-four-week placebo-controlled dose-ranging study.

Author: AllgulanderC, HackettD, SalinasE

GAD treatment
Discontinuation rate

Venlafaxine extended release (ER) was found to be an effective and safe treatment for generalized anxiety disorder (GAD) for up to 6 months. All doses of venlafaxine ER showed efficacy superior to placebo, and the discontinuation rate did not differ significantly among the treatment groups.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

11.

Kava extract for treating anxiety.

Author: PittlerM H, ErnstE

Anxiety treatment

The study discussed the need for effective and safe treatment options for anxiety, as traditional treatments are often impractical due to resource constraints and synthetic anxiolytics often have adverse effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

12.

Does cognitive-behavioural therapy influence the long-term outcome of generalized anxiety disorder? An 8-14 year follow-up of two clinical trials.

Author: DurhamR C, ChambersJ A, MacDonaldR R, PowerK G, MajorK

CBT for anxiety

Cognitive behavior therapy (CBT) has been shown to be effective in treating generalized anxiety disorder in about 50% of cases, with benefits lasting for 6 to 12 months. This study investigates the potential long-term value of CBT.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

13.

The effects of deep diaphragmatic breathing and focused attention on dental anxiety in a private practice setting.

Author: BiggsQuinn M, KellyKimberly S, ToneyJ David

Breathing and focused attention for anxiety

This study compared the effectiveness of two self-taught anxiety reduction techniques—breathing and focused attention—with a control group in patients with high dental anxiety.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

14.

Differential response to placebo among patients with social phobia, panic disorder, and obsessive-compulsive disorder.

Author: HuppertJonathan D, SchultzLuke T, FoaEdna B, BarlowDavid H, DavidsonJonathan R T, GormanJack M, ShearM Katherine, SimpsonH Blair, WoodsScott W

Placebo effect

Patients with obsessive-compulsive disorder are less likely to respond to placebo than patients with social phobia or panic disorder.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

15.

The treatment of social anxiety disorder.

Author: RodebaughThomas L, HolawayRobert M, HeimbergRichard G

Social anxiety disorder treatment

This review examines available treatments for social anxiety disorder, focusing on psychotherapeutic interventions for adults and outlining the need for further research into predictors of treatment response and the potential benefits of combining cognitive-behavioral therapy (CBT) and medication.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Language : English

16.

Remission rates in patients with anxiety disorders treated with paroxetine.

Author: BallengerJames C

Treatment of depression and anxiety

While about half of people with depression or anxiety respond to treatment, only a small percentage achieve complete remission. Continued mild symptoms even after treatment increases the risk of relapses and higher healthcare use. The goal of treatment should be complete remission, not just improvement, for both depression and anxiety.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Language : English

17.

Effects of a transdiagnostic group treatment for anxiety on secondary depression.

Author: NortonPeter J, HayesSarah A, HopeDebra A

Anxiety treatment
Depressive mood reduction

The study found that clients undergoing transdiagnostic treatment for anxiety experienced significant decreases in depressed mood compared to wait-list control participants.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

18.

Alprazolam (Xanax, and others) revisited.

Author:

Anxiety treatment
Panic disorder treatment
Abuse potential
Sedation
Withdrawal symptoms

Alprazolam, a benzodiazepine, is effective for anxiety and panic disorder but can cause sedation, withdrawal symptoms, and abuse. SSRIs are a safer alternative, and cognitive-behavioral therapy may be more effective in the long term.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

19.

The efficacy of antidepressants for generalized anxiety disorder: a systematic review and meta-analysis.

Author: SchmittRicardo, GazalleFernando Kratz, LimaMaurício Silva de, CunhaAngelo, SouzaJuliano, KapczinskiFlávio

Anxiety reduction
Dropout

Antidepressants are likely to be an effective treatment for generalized anxiety disorder.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

20.

Treatment of anxiety disorders in primary care practice: a randomised controlled trial.

Author: van BoeijenChristine A, van OppenPatricia, van BalkomAnton J L M, VisserSako, KempePieter T, BlankensteinNettie, van DyckRichard

Anxiety reduction
Feasible primary care

This study found that primary care patients with prevalent anxiety disorders can be adequately treated by their general practitioners, either with guided self-help or the Anxiety Disorder Guidelines.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

21.

A pragmatic, unblinded randomised controlled trial comparing an occupational therapy-led lifestyle approach and routine GP care for panic disorder treatment in primary care.

Author: LambertRodney A, HarveyIan, PolandFiona

Improved anxiety treatment
Anxiety

The number of people receiving treatment for anxiety in the UK has increased by over 30% since 1994. While medication and therapy are the most common treatments, outcomes are sometimes poor with frequent relapses. Lifestyle factors may play a role in anxiety, especially panic disorder, but are not addressed in treatment guidelines.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

22.

Cognitive self-therapy for chronic depression and anxiety: a multi-centre randomized controlled study.

Author: den BoerPeter C A M, WiersmaDurk, Ten VaarwerkInge, SpanMark M, StantA Dennis, Van den BoschRobert J

Improved social functions
Reduced symptoms

The study investigated the effectiveness of cognitive self-therapy (CST) in the treatment of depression or generalized anxiety disorder. The results showed that both CST and treatment as usual (TAU) led to significant improvement in symptoms, but there was no difference between the two conditions. CST was associated with lower medical care utilization, suggesting that it may be a cost-effective alternative for managing chronic depression and anxiety disorders.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

23.

The pharmacological management of childhood anxiety disorders: a review.

Author: ReinblattShauna P, RiddleMark A

Pediatric anxiety treatment

Psychopharmacological treatments for pediatric anxiety have expanded, with increasing evidence guiding current clinical practice.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

24.

Psychological therapies for generalised anxiety disorder.

Author: HunotV, ChurchillR, Silva de LimaM, TeixeiraV

CBT effective

This review examined the efficacy and acceptability of psychological therapies for patients with generalized anxiety disorder (GAD). The review found that psychological therapy based on CBT principles is effective in reducing anxiety symptoms for short-term treatment of GAD. Further studies examining non-CBT models are required to inform health care policy on the most appropriate forms of psychological therapy in treating GAD.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

25.

Anxiety symptom focus in sessions of cognitive therapy for depression.

Author: GibbonsCarly J, DeRubeisRobert J

Depression treatment
Anxiety exacerbation

This study investigated the effect of comorbid anxiety on cognitive therapy for depression.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

26.

Reducing anxiety sensitivity with exercise.

Author: SmitsJasper A J, BerryAngela C, RosenfieldDavid, PowersMark B, BeharEvelyn, OttoMichael W

Reduced anxiety sensitivity

The role of exercise in reducing fears of anxiety-related sensations (anxiety sensitivity) was examined.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

27.

Pain interference impacts response to treatment for anxiety disorders.

Author: TehCarrie Farmer, MoroneNatalia E, KarpJordan F, BelnapBea Herbeck, ZhuFang, WeinerDebra K, RollmanBruce L

Pain interference

Pain that interferes with daily activities is prevalent in primary care patients with panic disorder or generalized anxiety disorder. It is associated with more severe anxiety, worse daily functioning, higher healthcare use, and a lower likelihood of responding to anxiety treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

28.

Pharmacotherapy for anxiety disorders in children and adolescents.

Author: IpserJonathan C, SteinDan J, HawkridgeSusan, HoppeLara

Medication for anxiety

Anxiety disorders are prevalent in children and adolescents, leading to increased interest in medication for treating these conditions in this age group.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

29.

A placebo-controlled trial of phenelzine, cognitive behavioral group therapy, and their combination for social anxiety disorder.

Author: BlancoCarlos, HeimbergRichard G, SchneierFranklin R, FrescoDavid M, ChenHenian, TurkCynthia L, VermesDonna, ErwinBrigette A, SchmidtAndrew B, JusterHarlan R, CampeasRaphael, LiebowitzMichael R

Combined treatment social anxiety

This randomized, double-blind, placebo-controlled trial examined the effectiveness of combined medication (phenelzine sulfate) and cognitive behavioral group therapy (CBGT) for treating social anxiety disorder in 128 individuals. Combined treatment was superior to either monotherapy or placebo in reducing symptoms and achieving response and remission.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

30.

Hydroxyzine for generalised anxiety disorder.

Author: GuaianaGiuseppe, BarbuiCorrado, CiprianiAndrea

Reduced anxiety symptoms

Hydroxyzine, an antihistamine, has been explored for its potential in managing generalized anxiety disorder, alongside established treatments like cognitive behavioral therapy and antidepressants.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

31.

Second-generation antipsychotics for anxiety disorders.

Author: DeppingAnna M, KomossaKatja, KisslingWerner, LeuchtStefan

Anxiety management
Side effects

This review of 11 randomized controlled trials found that quetiapine was efficacious in reducing symptoms of generalized anxiety disorder, with a similar effect to antidepressants. However, quetiapine was associated with lower tolerability.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

32.

Acceptance-based behavioral therapy for GAD: effects on outcomes from three theoretical models.

Author: TreanorMichael, ErismanShannon M, Salters-PedneaultKristalyn, RoemerLizabeth, OrsilloSusan M

CBT for GAD
Treatment limitations

While cognitive-behavioral therapy (CBT) is effective for generalized anxiety disorder, many individuals remain symptomatic, highlighting the need for further treatment development.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

33.

Anxiety as a predictor of improvements in somatic symptoms and health anxiety associated with cognitive-behavioral intervention in hypochondriasis.

Author: NakaoMutsuhiro, ShinozakiYasuko, AhernDavid K, BarskyArthur J

Reduced anxiety
Reduced hypochondriasis

Cognitive-behavioral therapy (CBT) has been shown to be an effective treatment for hypochondriasis. A study of 182 hypochondriacal participants found that high anxiety at the outset of treatment predicted a better treatment outcome for CBT.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

34.

Mind-body interventions during pregnancy for preventing or treating women's anxiety.

Author: MarcIsabelle, TourecheNarimane, ErnstEdzard, HodnettEllen D, BlanchetClaudine, DodinSylvie, NjoyaMerlin M

Improved pregnancy anxiety treatment

This study discusses the prevalence of anxiety during pregnancy and its potential impact on the course of pregnancy and child development. It explores the use of non-pharmacological interventions like mind-body techniques to manage and prevent anxiety in pregnant women.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

35.

Transdiagnostic versus diagnosis-specific cbt for anxiety disorders: a preliminary randomized controlled noninferiority trial.

Author: NortonPeter J, BarreraTerri L

Effective treatment for anxiety disorders

Transdiagnostic cognitive-behavioral treatments for anxiety disorders have shown promise in open trials, but more rigorous research is needed. This abstract highlights the need for studies comparing transdiagnostic anxiety treatments to standard treatments, waitlist conditions, or published benchmarks to fully understand their efficacy.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

36.

Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study.

Author: AmsterdamJay D, ShultsJustine, SoellerIrene, MaoJun James, RockwellKenneth, NewbergAndrew B

Effective treatment for anxiety and depression

Anxiety and depression are common conditions affecting a significant portion of the population. While conventional drug therapies are available, many individuals remain untreated due to various reasons. This emphasizes the need for cost-effective and accessible alternative therapies for these conditions.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

37.

Thought Field Therapy (TFT) as a treatment for anxiety symptoms: a randomized controlled trial.

Author: IrgensAudun, DammenToril, NysæterTor Erik, HoffartAsle

Anxiety treatment

Thought field therapy may have an enduring anxiety-reducing effect, as evidenced by significant decreases in anxiety and disability symptoms.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

38.

Hybrid cognitive behavioral therapy versus relaxation training for co-occurring anxiety and alcohol disorder: a randomized clinical trial.

Author: KushnerMatt G, MaurerEric W, ThurasPaul, DonahueChris, FryeBrenda, MenaryKyle R, HobbsJennifer, HaenyAngela M, Van DemarkJoani

Reduced alcohol use
Reduced anxiety

This study investigated the challenges of treating alcohol use disorder (AUD) in patients with co-occurring anxiety disorders. While adding anxiety treatment to AUD treatment didn't significantly improve alcohol outcomes, a cognitive behavioral therapy (CBT) program designed to address both anxiety and alcohol use showed promise in improving outcomes.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

39.

Effects of co-occurring depression on treatment for anxiety disorders: analysis of outcomes from a large primary care effectiveness trial.

Author: Campbell-SillsLaura, SherbourneCathy D, Roy-ByrnePeter, CraskeMichelle G, SullivanGreer, BystritskyAlexander, LangAriel J, ChaviraDenise A, RoseRaphael D, Shaw WelchStacy, SteinMurray B

Anxiety treatment

Depression is common in people seeking treatment for anxiety. This study found that depression can both predict and impact the effectiveness of anxiety treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

40.

Exercise for anxiety disorders: systematic review.

Author: JayakodyKaushadh, GunadasaShalmini, HoskerChristian

Reduced anxiety symptoms

Exercise may be effective as an adjunctive treatment for anxiety disorders, but it is less effective than antidepressant treatment. Both aerobic and non-aerobic exercise seem to reduce anxiety symptoms. Social phobics may benefit from exercise when combined with group CBT.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

41.

Pretreatment anxiety predicts patterns of change in cognitive behavioral therapy and medications for depression.

Author: ForandNicholas R, DerubeisRobert J

Depression treatment

Some studies suggest that anxiety at the beginning of treatment might hinder depression recovery. However, other studies show that anxiety can actually predict faster improvement in depression when treated with cognitive behavioral therapy (CBT). This study aims to further explore the complex relationship between anxiety and depression treatment, particularly how anxiety might influence the speed of recovery and the risk of relapse, and whether CBT has unique effects in this context.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

42.

Cognitive therapy for social anxiety disorder: the impact of the "self-focused attention and safety behaviours experiment" on the course of treatment.

Author: SchreiberFranziska, HeimlichChristiane, SchweitzerClea, StangierUlrich

Anxiety reduction

This study will examine the impact of a cognitive therapy intervention called the 'self-focused attention and safety behaviors experiment' on treatment outcomes for social anxiety disorder (SAD).

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

43.

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults.

Author: Mayo-WilsonEvan, MontgomeryPaul

Media-delivered interventions
Self-help
Anxiety disorders

Anxiety disorders are the most common mental health problems and are often chronic. While effective treatments exist, access to services is limited. Media-delivered behavioral and cognitive behavioral interventions (self-help) offer a way to provide treatment with less professional input compared to traditional therapies.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

44.

Anxiety: a systematic review of neurobiology, traditional pharmaceuticals and novel alternatives from medicinal plants.

Author: GelfusoÉrica Aparecida, RosaDaiane Santos, FachinAna Lúcia, MortariMárcia Renata, CunhaAlexandra Olimpio Siqueira, BeleboniRene Oliveira

Anxiety control

This review will discuss the current understanding of anxiety disorders, including epidemiology, classification, pharmacological treatments, neurobiology, and animal models.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

45.

Cognitive-behavioral therapy for anxious children: from evidence to practice.

Author: SawyerMonique C, NunezDiane E

Reduced anxiety

While cognitive-behavioral therapy (CBT) is recommended as a first-line treatment for childhood anxiety, current practice often falls short due to issues of feasibility, affordability, and transportability.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

46.

Pre-treatment child and family characteristics as predictors of outcome in cognitive behavioural therapy for youth anxiety disorders.

Author: Lundkvist-HoundoumadiIrene, HougaardEsben, ThastumMikael

Anxiety treatment
High non-response rate

Cognitive behavioral therapy (CBT) is effective for children and adolescents with anxiety disorders, but a significant number do not respond. Identifying pre-treatment characteristics that predict treatment outcome is crucial for improving patient care.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

47.

Randomized clinical trial evaluating the efficacy of a brief intervention targeting anxiety sensitivity cognitive concerns.

Author: SchmidtNorman B, CapronDaniel W, RainesAmanda M, AllanNicholas P

AS treatment

Anxiety sensitivity (AS), a tendency to worry about the consequences of anxiety, is a risk factor for anxiety and other mental health problems. AS can be broken down into concerns about physical sensations, social situations, and thoughts. Cognitive concerns about anxiety have been linked to suicide. While treatments have been developed to reduce AS, they often focus on the physical component. This study aims to create and evaluate a treatment that specifically targets the cognitive aspect of AS.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Language : English

48.

Telephone-delivered cognitive behavioral therapy for high anxiety sensitivity: a randomized controlled trial.

Author: OlthuisJanine V, WattMargo C, MackinnonSean P, StewartSherry H

Telephone-delivered CBT
Anxiety sensitivity

High anxiety sensitivity (AS) is associated with anxiety and depression. This study examines the effectiveness of a telephone-delivered cognitive behavioral therapy (CBT) intervention in reducing AS and associated symptoms. The research aims to provide a accessible and effective treatment approach for those struggling with high AS.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

49.

The impact of anxious symptoms in the remission of depressive symptoms in a clinical trial for depression: follow-up of six months.

Author: de Azevedo CardosoTaiane, MondinThaíse Campos, SpessatoBárbara Coiro, de Avila QuevedoLuciana, de Mattos SouzaLuciano Dias, da SilvaRicardo Azevedo, JansenKaren

Improved depression remission
Anxiety symptoms impact prognosis

Anxiety and depression are highly comorbid. This study examined the impact of anxiety symptoms on the remission of depressive symptoms after brief psychotherapy for depression.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

50.

[Acute pharmacotherapy for anxiety symptoms in patients with depression].

Author: QuanteA

Anxiety treatment
Benzodiazepine risks
Lack of studies

This review explores alternative treatment strategies for managing anxiety symptoms in depressed patients. While benzodiazepines are often used, they have significant drawbacks. The review discusses the potential benefits of quetiapine, olanzapine, olanzapine-fluoxetine combination, pregabalin, and silexan for this purpose.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : German

51.

Treatment of childhood anxiety disorder in the context of maternal anxiety disorder: a randomised controlled trial and economic analysis.

Author: CreswellCathy, CruddaceSusan, GerryStephen, GitauRachel, McIntoshEmma, MollisonJill, MurrayLynne, ShafranRosamund, SteinAlan, ViolatoMara, VoyseyMerryn, WillettsLucy, WilliamsNicola, YuLy-Mee, CooperPeter J

Improved child anxiety
None mentioned

Cognitive-behavioral therapy (CBT) for childhood anxiety disorders did not show significant benefit when supplemented with treatment for maternal anxiety disorders or maternal cognitions and behaviors. However, supplementing CCBT with treatment that targeted maternal cognitions and behaviours was a cost-effective use of resources.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

52.

Acceptance and commitment group therapy (ACT-G) for health anxiety: a randomized controlled trial.

Author: EilenbergT, FinkP, JensenJ S, RiefW, FrostholmL

ACT-G for health anxiety

Severe health anxiety is common, but often goes undiagnosed and untreated. This study investigated the effectiveness of acceptance and commitment group therapy (ACT-G) compared to a waiting list for people with severe health anxiety.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

53.

Development and randomized trial evaluation of a novel computer-delivered anxiety sensitivity intervention.

Author: CapronDaniel W, SchmidtNorman B

Cost effective treatment
Increased dissemination
Reduced anxiety

A computer-based treatment for anxiety sensitivity (AS) was developed and tested. The treatment used a cognitive bias modification for interpretation biases (CBM-I) approach, which aims to change how people interpret ambiguous situations. A context-shifting task was used to deliver twice the treatment dose of existing interventions.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

54.

Cognitive mechanisms of diazepam administration: a healthy volunteer model of emotional processing.

Author: PringleA, WarrenM, GottwaldJ, CowenP J, HarmerC J

Anxiety relief

Benzodiazepines continue to be prescribed for anxiety disorders, particularly when other treatments fail or rapid relief is needed. However, the neuropsychological mechanism by which these drugs relieve anxiety symptoms remains unclear.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

55.

False Safety Behavior Elimination Therapy: A randomized study of a brief individual transdiagnostic treatment for anxiety disorders.

Author: RiccardiChristina J, KorteKristina J, SchmidtNorman B

Treatment for anxiety disorders

This study tested the efficacy of a brief, transdiagnostic treatment (F-SET) for anxiety disorders, targeting anxiety-maintaining behaviors and cognitive strategies.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

57.

Combined "top-down" and "bottom-up" intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification.

Author: CapronDaniel W, NorrAaron M, AllanNicholas P, SchmidtNorman B

Anxiety disorder treatment
Anxiety sensitivity reduction
None mentioned

This study evaluated the effect of adding an interpretation bias modification (CBM-I) intervention to an anxiety sensitivity (AS) psychoeducation intervention.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

58.

Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial.

Author: MaoJun J, XieSharon X, KeefeJohn R, SoellerIrene, LiQing S, AmsterdamJay D

Reduced GAD symptoms
Safe
Did not significantly reduce relapse rate
Limited sample size

This two-phase study evaluated the long-term use of chamomile for preventing GAD symptom relapse. Chamomile was safe and significantly reduced moderate-to-severe GAD symptoms but did not significantly reduce the rate of relapse. Further research is needed to confirm potential superiority over placebo.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

59.

ECT-Related Anxiety: A Systematic Review.

Author: ObbelsJasmien, VerwijkEsmée, BouckaertFilip, SienaertPascal

ECT adherence
ECT anxiety

This study discusses the under-reported issue of anxiety in patients receiving electroconvulsive therapy (ECT).

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

60.

A randomized clinical trial targeting anxiety sensitivity for patients with suicidal ideation.

Author: SchmidtNorman B, NorrAaron M, AllanNicholas P, RainesAmanda M, CapronDaniel W

Reduced AS

This research explores anxiety sensitivity (AS) as a risk factor for anxiety, mood disorders, and suicide. The study examines interventions aimed at reducing AS, including cognitive-behavioral skills and cognitive bias modification.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

61.

Can smartphone mental health interventions reduce symptoms of anxiety? A meta-analysis of randomized controlled trials.

Author: FirthJoseph, TorousJohn, NicholasJennifer, CarneyRebekah, RosenbaumSimon, SarrisJerome

Reduced anxiety

This study discussed the potential for smartphone-supported psychological interventions to reduce anxiety, although further research is needed to establish their role in managing anxiety disorders.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

62.

Disorder-specific versus generic cognitive-behavioral treatment of anxiety disorders in children and young people: a systematic narrative review of evidence for the effectiveness of disorder-specific CBT compared with the disorder-generic treatment, Coping Cat.

Author: Oldham-CooperRose, LoadesMaria

Anxiety disorder treatment

Coping Cat (CC), a cognitive-behavioral intervention, is recommended in the UK for anxiety disorders in children and adolescents. This abstract explores the use of CC for social anxiety disorder, generalized anxiety disorder, separation anxiety, and specific phobias, comparing it to disorder-specific approaches used in adults.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

63.

Randomized Pilot of an Anxiety Sensitivity-Based Intervention for Individuals in a Substance Use Day Program.

Author: WordenBlaise L, GenovaMarla, TolinDavid F

Anxiety reduction
Substance use reduction

This study investigated the preliminary efficacy of a brief intervention targeting anxiety sensitivity (AS) in individuals with substance use disorders. The intervention, which included interoceptive exposures, psychoeducation, and cognitive challenging, led to a short-term benefit in reducing AS, but this effect was not sustained at 3 months follow-up.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

65.

Exploring the pathway from anxiety sensitivity intervention to suicide risk reduction: Chained mediation through anxiety and depressive symptoms.

Author: NorrAaron M, AllanNicholas P, RegerGreg M, SchmidtNorman B

Reduced suicidal ideation

This study examines the mechanisms of suicidal ideation (SI) reduction due to a single-session, computerized intervention called the Cognitive Anxiety Sensitivity Treatment (CAST), which targets anxiety sensitivity (AS), a suicide risk factor.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

66.

The influence of comorbid anxiety on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder.

Author: van BronswijkSuzanne C, LemmensLotte H J M, HuibersMarcus J H, ArntzArnoud, PeetersFrenk P M L

Improved MDD treatment

This study examined the impact of comorbid anxiety disorders and symptoms on the effectiveness and dropout rates during cognitive therapy (CT) and interpersonal psychotherapy (IPT) for major depressive disorder (MDD), exploring the role of anxiety in MDD treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

67.

Enduring effects of psychological treatments for anxiety disorders: meta-analysis of follow-up studies.

Author: BandelowBorwin, SagebielAnne, BelzMichael, GörlichYvonne, MichaelisSophie, WedekindDirk

Anxiety treatment

This abstract discusses the long-term effects of psychotherapy versus control groups for anxiety disorders, highlighting the need for evidence on whether psychotherapy's enduring effects differ from those of control groups.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Language : English

68.

Effects of cognitive-behavioral therapy with relaxation vs. imagery rescripting on psychophysiological stress responses of students with test anxiety in a randomized controlled trial.

Author: ReissNeele, WarneckeIrene, TibubosAna Nanette, TolgouTheano, Luka-KrausgrillUrsula, RohrmannSonja

Reduced anxiety

A study of 180 university students with test anxiety found that cognitive behavioral therapy (CBT) and moderated self-help groups (SH) were successful in reducing self-reported state anxiety, but physiological stress responses remained unchanged.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

69.

The Scarier the Better: Maximizing Exposure Therapy Outcomes for Spider Fear.

Author: NorbergMelissa M, NewinsAmie R, JiangYan, XuJianqiu, ForcadellEduard, AlberichCristina, DeaconBrett J

Improved tolerance
Reduced fear

Adding an extra step to exposure therapy for spider phobia that directly challenged uncontrollability (Step 15: allowing a spider to walk freely over one's body) led to greater reductions in fear and fear beliefs. While some fear returned after a context change, participants who completed Step 15 maintained their ability to tolerate fear.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

70.

The effectiveness of art therapy for anxiety in adults: A systematic review of randomised and non-randomised controlled trials.

Author: AbbingAnnemarie, PonsteinAnne, van HoorenSusan, de SonnevilleLeo, SwaabHanna, BaarsErik

Anxiety disorders treatment
Art therapy

Anxiety disorders are common and are typically treated with therapy and medications. While some people don't respond well to standard treatments, art therapy is also used, but there is a lack of evidence on its effectiveness in reducing anxiety symptoms. This review aims to examine the research on art therapy for anxiety to better understand how it works and whether it is effective.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

71.

A randomised controlled trial of treatments of childhood anxiety disorder in the context of maternal anxiety disorder: clinical and cost-effectiveness outcomes.

Author: CreswellCathy, ViolatoMara, CruddaceSusan, GerryStephen, MurrayLynne, ShafranRoz, SteinAlan, WillettsLucy, McIntoshEmma, CooperPeter J

Child anxiety reduction
Maternal anxiety reduction

Child-focused CBT with nonspecific control interventions, child-focused CBT with CBT for maternal anxiety disorder, and child-focused CBT with an intervention targeting the mother-child interaction demonstrated good outcomes for children and their mothers with anxiety disorders. The addition of an intervention targeting the mother-child interaction may be cost-effective.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

72.

Symptom-specific effects of cognitive-behavioral therapy, sertraline, and their combination in a large randomized controlled trial of pediatric anxiety disorders.

Author: CervinMatti, StorchEric A, PiacentiniJohn, BirmaherBoris, ComptonScott N, AlbanoAnne Marie, GoschElizabeth, WalkupJohn T, KendallPhilip C

Reduced anxiety symptoms

Cognitive-behavioral therapy (CBT), sertraline, and their combination all demonstrated beneficial effects in pediatric anxiety disorders, primarily through a reduction of psychological distress, family interference, and avoidance.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

73.

Guided Imagery: Reducing Anxiety, Depression, and Selected Side Effects Associated With Chemotherapy.

Author: MahdizadehMohammad J, TirgariBatool, AbadiOm S R R, BahaadinbeigyKambiz

Improved side effects
Reduced anxiety
Reduced depression
None

Guided imagery significantly decreased anxiety and depression in patients with cancer undergoing chemotherapy, compared to a control group.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

74.

A multimethod investigation of the impact of attentional control on a brief intervention for anxiety and depression.

Author: AllanNicholas P, AlbaneseBrian J, JudahMatt R, GoochCaroline V, SchmidtNorman B

Reduced anxiety
Reduced depression

This study investigates the moderating effects of attentional control on the efficacy of a brief anxiety sensitivity (AS) intervention. The study examines both self-reported and neurophysiological indices of attentional control.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

75.

Efficacy of an acceptance-based group behavioral therapy for generalized anxiety disorder.

Author: de Almeida SampaioThiago Pacheco, JorgeRenê Cabral, MartinsDaniel Santos, GandarelaLucas Marques, Hayes-SkeltonSarah, BernikMárcio Antonini, Lotufo-NetoFrancisco

Improved GAD outcome

This study compared the effectiveness of acceptance-based group behavioral therapy (ABBT), combining mindfulness and exposure strategies, with standard nondirective supportive group therapy (NDST) for generalized anxiety disorder (GAD) in a Brazilian anxiety disorders program.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

76.

Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial.

Author: AxelssonErland, AnderssonErik, LjótssonBrjánn, BjörkanderDaniel, Hedman-LagerlöfMaria, Hedman-LagerlöfErik

Health anxiety treatment
Increased access to care
None reported

Internet-delivered CBT was found to be noninferior to face-to-face CBT for health anxiety, while incurring lower societal costs. The study supports the potential of online treatment formats to improve access to evidence-based treatment for health anxiety.

Equivalence TrialA clinical trial designed to show that a new treatment is equivalent in efficacy/safety to an existing treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

77.

Cognitive-behavioural interventions for prevention and treatment of anxiety in young children: A systematic review and meta-analysis.

Author: Howes VallisEmily, ZwickerAlyson, UherRudolf, PavlovaBarbara

Improved anxiety treatment

This study highlights the importance of early prevention and treatment for anxiety disorders in preschool children, given their potential impact on emotional development and school readiness.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

78.

Blended Acceptance and Commitment Therapy Versus Face-to-face Cognitive Behavioral Therapy for Older Adults With Anxiety Symptoms in Primary Care: Pragmatic Single-blind Cluster Randomized Trial.

Author: WitloxMaartje, GarnefskiNadia, KraaijVivian, de WaalMargot W M, SmitFilip, BohlmeijerErnst, SpinhovenPhilip

Anxiety treatment

Anxiety is common and debilitating in older adults, but many don't receive treatment. While face-to-face cognitive behavioral therapy (CBT) has shown promise, this study calls for exploring other treatment approaches and ways to deliver therapy, such as online or group sessions, to reach more people with anxiety.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Pragmatic Clinical TrialA trial conducted in a real-world clinical setting. It evaluates the effectiveness of interventions in everyday healthcare environments.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

79.

Vortioxetine for generalised anxiety disorder in adults.

Author: MezaNicolás, LeytonFanny

Nausea

This systematic review found limited evidence to determine whether vortioxetine is effective in treating generalized anxiety disorder in adults. While the certainty of the evidence was very low, there was some uncertainty whether vortioxetine increases the response to treatment or improves anxious symptoms. Vortioxetine may increase nausea.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Language : Spanish

80.

A Sequential Multiple Assignment Randomized Trial (SMART) study of medication and CBT sequencing in the treatment of pediatric anxiety disorders.

Author: PetersonBradley S, WestAmy E, WeiszJohn R, MackWendy J, KipkeMichele D, FindlingRobert L, MittmanBrian S, BansalRavi, PiantadosiSteven, TakataGlenn, KoebnickCorinna, AshenCeth, SnowdyChristopher, PoulsenMarie, AroraBhavana Kumar, AllemCourtney M, PerezMarisa, MarcyStephanie N, HudsonBradley O, ChanStephanie H, WeersingRobin

Medication for anxiety
Psychotherapy for anxiety

Medication and psychotherapy are both effective treatments for anxiety disorders in children, but there is limited research comparing their effectiveness head-to-head. More research is needed to determine the best course of treatment for children whose initial treatment is ineffective.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

81.

Efficacy of temporally intensified exposure for anxiety disorders: A multicenter randomized clinical trial.

Author: PittigAndre, HeinigIngmar, GoerigkStephan, ThielFreya, HummelKatrin, SchollLucie, DeckertJürgen, PauliPaul, DomschkeKatharina, LuekenUlrike, FydrichThomas, FehmLydia, PlagJens, StröhleAndreas, KircherTilo, StraubeBenjamin, RiefWinfried, KoelkebeckKatja, AroltVolker, DannlowskiUdo, MargrafJürgen, TotzeckChristina, SchneiderSilvia, NeudeckPeter, CraskeMichelle G, HollandtMaike, RichterJan, HammAlfons, WittchenHans-Ulrich

Anxiety reduction
Faster treatment

Temporally intensified exposure therapy (PeEx-I) with sessions condensed to 2 weeks showed faster treatment response, lower drop-out during the exposure phase, and no higher relapse than standard nonintensified exposure (PeEx-S) in 358 patients with severe anxiety disorders. Both treatments reduced symptom severity and disability.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

82.

Remotely Delivered Interventions to Support Women With Symptoms of Anxiety in Pregnancy: Mixed Methods Systematic Review and Meta-analysis.

Author: EvansKerry, Rennick-EgglestoneStefan, CoxSerena, KuipersYvonne, SpibyHelen

Reduced pregnancy anxiety

This abstract highlights the prevalence of anxiety during pregnancy and the potential benefits of remotely delivered low-level psychological therapy for mild to moderate anxiety symptoms. Remote interventions may improve access to care and provide a cost-effective, flexible approach to managing anxiety during pregnancy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

83.

Understanding the untreated course of anxiety disorders in treatment-seeking samples: A systematic review and meta-analysis.

Author: ScottAmelia J, BisbyMadelyne A, HeriseanuAndreea I, HathwayTaylor, KarinEyal, GandyMilena, DudeneyJoanne, StaplesLauren G, TitovNickolai, DearBlake F

Course of anxiety disorders

This meta-analysis studied the course of anxiety disorders in people who sought treatment by analyzing control groups from treatment studies. It aimed to understand how anxiety disorders progress when they are not treated, which is important information for treatment planning and evaluating treatment effectiveness.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

84.

Management strategies for adult patients with dental anxiety in the dental clinic: a systematic review.

Author: HoffmannB, ErwoodK, NcomanziS, FischerV, O'BrienD, LeeA

Behavioral strategies for dental anxiety
Pharmacological intervention side effects

This article discusses evidence-based strategies for mitigating dental anxiety. Dental anxiety is a common problem that can lead to avoidance of treatment, impacting both oral and general health. The article explores both behavioral and pharmacological approaches to manage dental anxiety.

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

85.

Comparison of Transdiagnostic Treatment and Specialized Social Anxiety Treatment for Children and Adolescents With Social Anxiety Disorder: A Randomized Controlled Trial.

Author: RapeeRonald M, McLellanLauren F, CarlTalia, TrompeterNora, HudsonJennifer L, JonesMichael P, WuthrichViviana M

CBT treatment for pediatric anxiety

This study compared a generic cognitive-behavioral therapy (CBT) treatment for pediatric anxiety with a modified treatment specifically targeting social anxiety. Pediatric social anxiety disorder typically has the poorest treatment response among anxiety disorders.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

86.

Mindfulness-Based Stress Reduction vs Escitalopram for the Treatment of Adults With Anxiety Disorders: A Randomized Clinical Trial.

Author: HogeElizabeth A, BuiEric, MeteMihriye, DuttonMary Ann, BakerAmanda W, SimonNaomi M

MBSR for anxiety

This study explores the effectiveness of mindfulness-based interventions for treating anxiety disorders. Anxiety disorders are common and distressing, and mindfulness-based interventions are a popular treatment approach.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

87.

An analysis of differential improvement by diagnosis in group transdiagnostic cognitive behaviour therapy for anxiety disorders.

Author: RostamiMehrnaz, ProvencherMartin D, RobergePasquale, NortonPeter J

Anxiety reduction

This study aimed to examine whether participants with different principal anxiety diagnoses demonstrate similar anxiety reduction after receiving transdiagnostic cognitive behavior therapy (tCBT), a single protocol approach for treating anxiety disorders broadly.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Pragmatic Clinical TrialA trial conducted in a real-world clinical setting. It evaluates the effectiveness of interventions in everyday healthcare environments.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

88.

Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety.

Author: HaugeMariann Saanum, WillumsenTiril, StoraBent

Improved dental access
Reduced anxiety
Adverse effects

A dentist can implement systematic treatments for dental anxiety without increasing comorbid symptoms of anxiety, depression, or PTSD.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

89.

Targeting intolerance of uncertainty in treatment: A meta-analysis of therapeutic effects, treatment moderators, and underlying mechanisms.

Author: MillerMichelle L, McGuireJoseph F

Reduced anxiety symptom severity

This review found that evidence-based treatments for anxiety-related disorders can reduce intolerance of uncertainty (IU), which may improve anxiety symptoms.

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

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