Which role for antiplatelet and anticoagulant drugs in unstable angina pectoris?

Author: LewisH D

Paper Details 
Original Abstract of the Article :
Two large placebo-controlled, randomized, double-blind clinical trials have demonstrated the benefit of aspirin therapy in preventing myocardial infarction and death in patients with unstable angina. The Veterans Administration Cooperative Study of 1266 men hospitalized with unstable angina showed t...See full text at original site
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引用元:
https://doi.org/10.1007/BF00054259

データ提供:米国国立医学図書館(NLM)

Aspirin: A Potential Lifesaver for Unstable Angina

In the realm of cardiology, unstable angina, a warning sign of impending heart attack, poses a significant challenge. This study delves into the potential of aspirin as a preventative measure against myocardial infarction and death in patients experiencing this condition. Employing two large, placebo-controlled, randomized, double-blind clinical trials, the researchers meticulously investigated the effectiveness of aspirin therapy. Their findings revealed that aspirin, administered in daily doses, demonstrated a remarkable reduction in the incidence of myocardial infarction and mortality. This discovery could be a game-changer for patients with unstable angina, offering a glimmer of hope in a potentially perilous situation.

Aspirin's Impact: A Statistical Revelation

The data speaks volumes. The Veterans Administration Cooperative Study, involving a substantial cohort of 1266 men, demonstrated a 51% reduction in myocardial infarction (p=0.001) and a similar decrease in mortality. The Canadian McMaster University trial, with a sample size of 555 patients, corroborated these findings. Notably, the reduction in death alone was an impressive 71% (p=0.004). These statistically significant results underscore the profound impact of aspirin therapy in mitigating the risks associated with unstable angina.

Aspirin: A Beacon of Hope for Unstable Angina

This research sheds light on the potentially life-saving benefits of aspirin for patients with unstable angina. It suggests that daily aspirin intake could play a critical role in preventing heart attacks and reducing mortality. It's a testament to the power of simple interventions in combating complex medical conditions. Like a traveler finding an oasis in a vast desert, patients with unstable angina could find solace and hope in this new understanding of aspirin's potential.

Dr.Camel's Conclusion

My dear friends, the sands of time have shifted, revealing a new understanding of aspirin's role in heart health. This research is like a beacon of hope in the vast desert of unstable angina, offering a potential lifeline to patients battling this condition. It is a reminder that even in the face of seemingly insurmountable challenges, science can deliver solutions that improve our lives.
Date :
  1. Date Completed 1991-04-26
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3154685

DOI: Digital Object Identifier

10.1007/BF00054259

Related Literature

SNS
PICO Info
in preparation
Languages

English

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