Combination Lorcaserin and Nicotine Patch for Smoking Cessation Without Weight Gain.

Author: DavisJames M, RoseJed E

Overview

The combination of lorcaserin and nicotine patch was well-tolerated and associated with a 31.1% smoking abstinence rate within 7 to 10 weeks post-quit attempt. It also effectively prevented weight gain associated with smoking cessation.

Paper Details　

Original Abstract of the Article :

INTRODUCTION: This study explored the efficacy of combination lorcaserin and nicotine patch for smoking cessation treatment and prevention of postsmoking cessation weight gain. METHODS: We conducted a trial in which 61 adult daily smokers were asked to quit smoking using a combination of lorcaserin...See full text at original site

Dr.Camel's Paper Summary Blog

Lorcaserin and Nicotine Patch: A Double-Edged Sword for Smoking Cessation

This study investigates the effectiveness of a combination therapy for smoking cessation, using lorcaserin, a medication that helps reduce appetite, and a nicotine patch, a common aid for quitting smoking. Imagine a camel in the desert, craving the refreshing taste of water, but aware of the dangers of relying solely on a mirage. This study aims to explore a balanced approach to quitting smoking, combining a medication that addresses cravings and another that provides nicotine replacement therapy.

The researchers conducted a study involving 61 adult smokers, randomly assigning them to receive either lorcaserin plus a nicotine patch or a placebo plus a nicotine patch for 12 weeks. They monitored the participants' smoking abstinence rates and weight changes throughout the study.

The study found that the combination of lorcaserin and a nicotine patch was effective in reducing smoking and preventing weight gain. The researchers observed a significant smoking abstinence rate, and the participants did not experience weight gain after quitting smoking. This suggests that this combination therapy could be a valuable option for smokers who struggle with both quitting smoking and managing their weight.

A Balanced Approach to Quitting: Navigating the Mirage of Weight Gain

The study's findings offer hope for smokers who are hesitant to quit because of concerns about weight gain. The combination of lorcaserin and a nicotine patch may offer a more balanced approach, helping to address cravings and prevent weight gain, leading to a smoother and more successful journey towards a smoke-free life.

Dr. Camel's Conclusion

Dr. Camel believes that this study presents a promising approach to smoking cessation, offering a balanced and effective combination therapy. The study's findings highlight the importance of addressing both the physical and psychological aspects of smoking cessation to ensure long-term success. Dr. Camel encourages smokers to discuss these options with their healthcare provider and explore the potential benefits of a combination therapy. Remember, a successful journey through the desert of addiction requires a comprehensive and personalized approach to overcome challenges and reach a healthier destination.