Paper Details 
Original Abstract of the Article :
Antiviral susceptibility screening of avian influenza (AI) H9N2 viruses is crucial considering their role at the animal-human interface and potential to cause human infections. The Matrix 2 (M2) inhibitors (amantadine and rimantadine) have been used for prophylaxis and treatment of influenza A virus...See full text at original site
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引用元:
https://doi.org/10.1016/j.micpath.2019.103779

データ提供:米国国立医学図書館(NLM)

Amantadine Resistance Markers Among Low Pathogenic Avian Influenza H9N2 Viruses

The world of influenza viruses is a vast and ever-changing desert, with new strains emerging and adapting constantly. This study, like a vigilant scientist, explores the emergence of amantadine resistance in avian influenza H9N2 viruses, a significant threat to poultry health and potentially human health. The researchers meticulously analyzed the genetic sequences of these viruses, revealing the presence of mutations that confer resistance to this antiviral drug.

The Evolving Landscape of Influenza Virus Resistance

This study highlights the dynamic nature of influenza virus evolution, a constant battle between viruses and antiviral drugs. The researchers found a significant increase in amantadine resistance among avian influenza H9N2 viruses, a worrying trend that underscores the need for vigilant monitoring and the development of new antiviral strategies. This research is like a warning sign in the desert, reminding us of the constant threat of emerging drug resistance and the need for proactive measures to combat this challenge.

The Importance of Antiviral Surveillance

This study emphasizes the importance of antiviral surveillance, a crucial tool for tracking the emergence and spread of drug resistance. The researchers' findings highlight the need for ongoing monitoring and the development of new antiviral drugs to maintain our defenses against this formidable foe. It is like a network of oases across the desert, providing essential resources for monitoring and combating the threat of drug resistance.

Dr.Camel's Conclusion

This study is a reminder that the battle against influenza viruses is an ongoing journey through the desert of evolution. The researchers have illuminated the emergence of amantadine resistance, a significant challenge that demands vigilant monitoring and the development of new antiviral strategies. This research is a call to action, urging us to remain vigilant in our fight against these formidable adversaries and to continue exploring new avenues for combatting this ever-evolving threat.

Date :
  1. Date Completed 2020-03-18
  2. Date Revised 2020-03-18
Further Info :

Pubmed ID

31600542

DOI: Digital Object Identifier

10.1016/j.micpath.2019.103779

Related Literature

SNS
PICO Info
in preparation
Languages

English

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