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Effects of Estrogen Replacement on Bone Geometry and Microarchitecture in Adolescent and Young Adult Oligoamenorrheic Athletes: A Randomized Trial.

Author: AckermanKathryn E, BouxseinMary L, EddyKamryn T, KlibanskiAnne, LeeHang, MisraMadhusmita, SinghalVibha, SlatteryMeghan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study compares the effects of transdermal 17β-estradiol versus oral ethinyl estradiol on bone microarchitecture in young oligoamenorrheic athletes. It finds that transdermal estrogen leads to greater improvements in bone structure, particularly at the tibia.
Paper Details　
Original Abstract of the Article :
Oligoamenorrheic athletes (OAs) have lower bone mineral density (BMD) and greater impairment of bone microarchitecture, and therefore higher fracture rates compared to eumenorrheic athletes. Although improvements in areal BMD (aBMD; measured by dual-energy X-ray absorptiometry) in OAs have been demo...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/31603998

データ提供：米国国立医学図書館（NLM）

Estrogen Replacement: A Boon for Bone Health in Adolescent and Young Adult Athletes

The realm of bone health, much like a vast and intricate network of canyons, requires a nuanced approach. This research focuses on the impact of estrogen replacement therapy on bone geometry and microarchitecture in adolescent and young adult athletes experiencing oligoamenorrhea, a condition characterized by irregular menstrual cycles. The researchers aimed to understand if estrogen replacement could help strengthen their bones, much like a sturdy bridge spanning a deep canyon.

Estrogen Replacement: A Potential Solution for Bone Loss in Athletes

This study's results, like a clear spring emerging from the heart of a canyon, demonstrate the positive effects of estrogen replacement therapy on bone health in athletes. The researchers found that transdermal estrogen treatment led to greater improvements in bone density and microarchitecture compared to oral estrogen or no treatment. This underscores the potential of estrogen replacement as a valuable tool for promoting bone health in athletes.

Maintaining Strong Bones: A Journey Through the Canyon of Health

This study emphasizes the importance of addressing bone health concerns in athletes, particularly those experiencing oligoamenorrhea. Estrogen replacement therapy, like a sturdy rope guiding climbers through a challenging canyon, can provide valuable support for maintaining bone health. However, it is crucial to consult with healthcare professionals to determine the most appropriate treatment plan.

Dr.Camel's Conclusion

This study sheds light on the potential benefits of estrogen replacement therapy in promoting bone health in adolescent and young adult athletes with oligoamenorrhea. The researchers' findings, like a beacon illuminating a treacherous canyon, provide valuable insights for managing bone health concerns in this population.

Date :
  1. Date Completed 2021-07-02
  2. Date Revised 2023-05-04
Further Info :

Pubmed ID

31603998

DOI: Digital Object Identifier

NIHMS1562691

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Languages

English

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