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A Systematic Review of Laboratory Evidence for the Abuse Potential of Tramadol in Humans.

Author: BergeriaCecilia L, DunnKelly E, HuhnAndrew S, StrainEric C

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Tramadol, an opioid analgesic, has a lower abuse potential compared to other opioids. Oral tramadol administered to individuals without opioid dependence showed the highest abuse potential. The abuse potential decreased with higher doses and parenteral administration.
Paper Details　
Original Abstract of the Article :
<b>Background:</b> Tramadol is an opioid-analgesic that has shown epidemiological evidence of abuse. This review evaluates the evidence for tramadol abuse potential in humans. <b>Methods:</b> A systematic literature search for human abuse liability examinations of tramadol was conducted in Septembe...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775208/

データ提供：米国国立医学図書館（NLM）

Tramadol Abuse Potential: A Review of Human Laboratory Evidence

The [opioid epidemic] has raised concerns about the [abuse potential] of various pain medications. This study examines the abuse potential of [tramadol], a commonly prescribed opioid analgesic. The researchers conducted a [systematic review] of human laboratory studies that compared tramadol to other opioids in terms of their abuse liability.

Tramadol's Abuse Potential: A Detailed Examination

The review found that tramadol's abuse potential was [lower than other opioids] to which it was compared. While tramadol did produce some [positive effects], it also produced [negative effects], and participants were less likely to identify it as an opioid. However, tramadol was associated with a [higher rate of self-administration] compared to other opioids in one study.

Navigating the Sands of Opioid Abuse

Understanding the abuse potential of different medications is crucial for managing the opioid epidemic. This study helps clinicians better understand the unique characteristics of tramadol and make informed decisions regarding its use.

Dr.Camel's Conclusion

This systematic review provides valuable insight into the abuse potential of tramadol. It highlights the importance of carefully considering the risks and benefits of all opioid medications, especially in the context of the current opioid epidemic.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-02-24
Further Info :

Pubmed ID

31616329

DOI: Digital Object Identifier

PMC6775208

Related Literature

Article Analysis
・Effects of tramadol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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