Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta-analysis.

Author: ChangS E, ChoiJ H, JungC J, JungJ M, LeeM W, LeeW J, WonC H

Paper Details 
Original Abstract of the Article :
Selecting a topical treatment from among the numerous topical agents for external genital warts remains challenging without clear evidence. Our aim was to evaluate comparatively the efficacy and safety of topical agents for external genital warts using a network meta-analysis. We included all random...See full text at original site
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引用元:
https://doi.org/10.1111/bjd.18638

データ提供:米国国立医学図書館(NLM)

Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta-analysis

The realm of [Dermatology] is constantly seeking effective and safe treatments for [External genital warts]. This research aims to evaluate the comparative efficacy and safety of various [Topical treatments] for [External genital warts] in [Nonimmunocompromised patients]. The researchers conducted a comprehensive [Systematic review] and [Network meta-analysis] of existing clinical trials to assess the relative benefits and risks of different topical agents. The findings offer valuable insights into the best treatment options for patients with [External genital warts].

Comparative Effectiveness of Topical Treatments

The study reveals that [Podophyllotoxin 0·5% solution] is significantly more efficacious than [Imiquimod 5% cream] for [Lesion clearance], but is associated with a higher [Adverse event rate]. [Sinecatechins 15% ointment] is significantly less efficacious than [Imiquimod 5% cream]. Other treatments, such as [Idoxuridine, polyhexamethylene biguanide, cidofovir, and SB206], demonstrate comparable efficacy to conventional therapies. These findings provide valuable guidance for [Dermatologists] selecting the most appropriate topical treatment based on individual patient needs and risk tolerance.

Navigating the Sands of Warts

This research provides valuable information for [Patients with external genital warts] and [Healthcare providers] involved in their care. It highlights the importance of [Considering different treatment options] and discussing potential benefits and risks with a healthcare professional. The study underscores the need for [Continued research] to further evaluate the efficacy and safety of [Topical treatments] and develop novel approaches for managing [External genital warts].

Dr. Camel's Conclusion

Just as a camel adapts to the harsh desert environment, [Patients with external genital warts] can find relief with the right treatment approach. This research provides a roadmap for [Dermatologists], highlighting the comparative effectiveness of various [Topical treatments]. It emphasizes the importance of [Personalized care] and [Continued research] in the quest for safe and effective therapies for [External genital warts].

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

31675442

DOI: Digital Object Identifier

10.1111/bjd.18638

Related Literature

SNS
PICO Info
in preparation
Languages

English

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