Trajectory classes of opioid use among individuals in a randomized controlled trial comparing extended-release naltrexone and buprenorphine-naloxone.

Author: Barbosa-LeikerCelestina, BurlewKathleen, CampbellAimee N C, FitzpatrickSkye, GreenfieldShelly F, NunesEdward V, PavlicovaMartina, RotrosenJohn, RuglassLesia M, ScodesJennifer

Paper Details 
Original Abstract of the Article :
To advance our understanding of medication treatments for opioid use disorders (OUDs), identification of distinct subgroups and factors associated with differential treatment response is critical. We examined trajectories of opioid use for patients with OUD who were randomized to (but not in all cas...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/31704382

データ提供:米国国立医学図書館(NLM)

Distinct Trajectories of Opioid Use: Identifying Subgroups and Factors Associated with Treatment Response

Opioid use disorder (OUD) continues to be a major public health concern. This research investigates the trajectories of opioid use in patients with OUD who are randomized to either buprenorphine-naloxone (BUP-NX) or extended-release naltrexone (XR-NTX). The authors aim to identify distinct subgroups of patients and the factors associated with differential treatment response.

Unveiling Heterogeneity in Treatment Response: A Deeper Understanding of OUD

The findings reveal that patients with OUD exhibit diverse trajectories of opioid use, with certain characteristics being associated with specific treatment outcomes. This research underscores the importance of personalized treatment approaches, tailored to individual needs and characteristics.

Navigating the Complexities of Opioid Use Disorder: A Call for Tailored Interventions

This study emphasizes the need for a more nuanced understanding of OUD and the factors that influence treatment response. By identifying distinct subgroups of patients, healthcare professionals can develop more effective and individualized interventions to address the challenges posed by this complex disorder.

Dr. Camel's Conclusion

The path to recovery from OUD is as winding and unpredictable as a desert sandstorm. This research provides valuable insights into the different trajectories of opioid use and the factors that influence treatment success. By understanding this heterogeneity, we can better guide patients on their journey to recovery.

Date :
  1. Date Completed 2020-07-06
  2. Date Revised 2020-12-01
Further Info :

Pubmed ID

31704382

DOI: Digital Object Identifier

NIHMS1545082

Related Literature

SNS
PICO Info
in preparation
Languages

English

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