Risks and management of antiepileptic drug induced skin reactions in the adult out-patient setting.

Author: BansalAmolak S, FowlerThomas, LozsádiDora

Paper Details 
Original Abstract of the Article :
Adverse cutaneous reactions caused by mostly aromatic antiepileptic drugs (AED) affect 50.000 people a year in the United Kingdom (UK; incidence 75.7/100.000). Optimal management of these cases is often difficult, as the patient may report symptoms to a general practitioner, attend Accident & Emerge...See full text at original site
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引用元:
https://doi.org/10.1016/j.seizure.2019.07.003

データ提供:米国国立医学図書館(NLM)

Skin Reactions from Antiepileptic Drugs: A Desert of Challenges

The field of [epilepsy treatment] faces a challenging landscape when it comes to [managing skin reactions caused by antiepileptic drugs (AEDs)]. This research delves into the desert of [understanding the risks and management of AED-induced skin reactions in adult outpatients]. The authors employed [a comprehensive review of published data and clinical experience] to navigate this complex terrain. Their study aims to illuminate [a pragmatic management pathway for patients suffering a suspected drug-induced rash]. Notably, they highlight [the importance of early identification of patients at risk of developing severe allergic reactions] and provide [UK pretreatment screening guidelines, a step-by-step clinical assessment of rash, and associated symptoms].

The Importance of Early Detection

This research reveals that [approximately 50,000 people in the UK experience adverse cutaneous reactions from AEDs annually]. Early detection is crucial to avoid [unnecessary medication withdrawal, restricted treatment choices, and increased costs]. The authors emphasize that [a thorough assessment is essential to determine if the rash is truly drug-induced or a consequence of other factors].

Navigating the Desert of AEDs

For patients with suspected AED-induced skin reactions, this research provides valuable guidance to [avoid unnecessary medication withdrawal and ensure appropriate treatment]. The authors recommend [a careful evaluation of the rash and associated symptoms, followed by a tailored approach to medication management].

Dr.Camel's Conclusion

This research sheds light on a critical aspect of [epilepsy treatment] in the vast desert of [pharmacological management]. The authors provide a roadmap for clinicians to [effectively manage AED-induced skin reactions], ensuring patients receive [optimal treatment while minimizing risks].

Date :
  1. Date Completed 2020-06-26
  2. Date Revised 2020-06-26
Further Info :

Pubmed ID

31708349

DOI: Digital Object Identifier

10.1016/j.seizure.2019.07.003

SNS
PICO Info
in preparation
Languages

English

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