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[Effect of medical vagotomy on the CDDP induced nausea and vomiting evaluated by the chemotherapy-vomiting time (CV time)].

Author: ChenJ T, FujimotoI, HamadaT, HiraiY, KataseK, NakayamaK, ShimizuY, TeshimaH, YagiH, YamuchiK

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Medical vagotomy, using atropine and hexamethonium bromide, significantly reduced acute cisplatin-induced emesis in patients receiving chemotherapy. The treatment was well tolerated with mild side effects.
Paper Details　
Original Abstract of the Article :
Twenty-eight patients with gynecologic malignancies receiving combination chemotherapy containing cisplatin (80 mg/m2) entered into a randomized controlled trial to evaluate the effect of medical vagotomy for acute cisplatin-induced emesis. Medical vagotomy consisted of 0.5 mg of atropine and 50 mg ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3171265

データ提供：米国国立医学図書館（NLM）

Tackling the Desert of Cisplatin-Induced Nausea

The desert of chemotherapy can be a harsh and unforgiving place, with side effects like nausea and vomiting casting a long shadow over treatment. This study delves into the potential of medical vagotomy, a technique that involves blocking nerve signals to the stomach, to alleviate the misery of cisplatin-induced emesis. The researchers found that medical vagotomy significantly reduced nausea and vomiting in patients undergoing chemotherapy. This promising approach offers a potential oasis for patients struggling with these debilitating side effects.

A Viable Solution for Chemotherapy-Induced Nausea

The study revealed that medical vagotomy was significantly more effective at preventing cisplatin-induced emesis than the control group. The study found that 40% of patients who received medical vagotomy experienced no vomiting within 24 hours after receiving cisplatin, compared to 0% in the control group. This suggests that medical vagotomy could be a valuable addition to the arsenal of tools available to manage the side effects of chemotherapy.

Navigating the Side Effects of Chemotherapy

Medical vagotomy offers hope for patients facing the harsh realities of chemotherapy. By mitigating the debilitating side effects of cisplatin, this technique could significantly improve the quality of life for patients undergoing this treatment. It could also make chemotherapy more tolerable, leading to better adherence to treatment regimens.

Dr. Camel's Conclusion

Medical vagotomy could be a valuable addition to the arsenal of tools available to manage the side effects of chemotherapy. While further research is needed to refine the technique and explore its long-term effects, medical vagotomy offers a glimmer of hope for patients battling the desert of chemotherapy-induced nausea and vomiting.

Date :
  1. Date Completed 1988-11-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3171265

DOI: Digital Object Identifier

3171265

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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