[Local irritation studies of cefodizime sodium].

Author: ImamuraK, IrimuraK, KashiharaA, KoidaM, NakagawaM, ShinomiyaM, TanakaG, YamakitaO, YoshidaR

Paper Details 
Original Abstract of the Article :
Four local irritation studies of cefodizime sodium (THR-221), a new developed cephem-type antibiotics, were carried out with NZW rabbits. 1. In eye irritation test, 25% THR-221 water solution had no irritancy on eye mucosa in rabbits. 2. In single injective intramuscular irritation study, regardless...See full text at original site
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引用元:
https://doi.org/10.2131/jts.13.supplementi_257

データ提供:米国国立医学図書館(NLM)

Navigating the Irritation Landscape of Cefodizime Sodium

The world of antibiotics, like a vast desert with diverse flora and fauna, presents a constant challenge in balancing efficacy and safety. This research, like a meticulous desert explorer, examines the local irritation potential of cefodizime sodium, a newly developed antibiotic, seeking to understand its impact on various tissues.

The researchers, like skilled desert navigators, meticulously conducted four local irritation studies, carefully observing the effects of cefodizime sodium on rabbit eyes, muscles, and blood vessels.

Their findings, like a well-charted map revealing potential hazards, indicate that while cefodizime sodium can cause some irritation, particularly in the muscles and blood vessels, it is generally well-tolerated and shows promising recovery rates.

A Cautious Approach to Administration

The research suggests that while cefodizime sodium may cause some irritation, it is important to note that it does not pose a significant risk to patients. This finding, like discovering a safe passage through a treacherous desert, provides valuable insights for clinicians.

Navigating the Treatment Landscape

The study underscores the need for careful administration of cefodizime sodium, particularly avoiding repeated injections at the same site. This recommendation, like a warning sign in a hazardous desert, serves as a valuable reminder for clinicians to prioritize patient safety and optimize treatment outcomes.

Dr. Camel's Conclusion

This research provides a comprehensive assessment of the local irritation potential of cefodizime sodium. It's a reminder that the development and use of antibiotics requires a careful balance between efficacy and safety. This study, like a skilled desert guide, offers valuable insights for clinicians to navigate the complex landscape of antibiotic therapy.

Date :
  1. Date Completed 1988-11-23
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3172293

DOI: Digital Object Identifier

10.2131/jts.13.supplementi_257

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PICO Info
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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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