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Long-term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosis.

Author: Abou-SettaAhmed M, AriciAydin, BakerPhilip E, BeckerChristian, Garcia-VelascoJuan A, GeorgiouEktoras X, GranneIngrid E, MeloPedro, SallamHassan N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review investigates whether long-term gonadotropin-releasing hormone (GnRH) agonist therapy prior to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) can improve pregnancy outcomes in women with endometriosis.
Paper Details　
Original Abstract of the Article :
Endometriosis is known to have an impact on fertility and it is common for women affected by endometriosis to require fertility treatments, including in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI), to improve the chance of pregnancy. It has been postulated that long-term gon...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867786/

データ提供：米国国立医学図書館（NLM）

GnRH Agonist Therapy for Endometriosis and Fertility

The journey to parenthood can be a long and arduous one, especially for women struggling with endometriosis. This condition, like a desert mirage, can distort the landscape of fertility, making conception a difficult task. This review investigates the potential benefits of long-term GnRH agonist therapy, a treatment that can temporarily suppress ovulation, for women with endometriosis undergoing IVF or ICSI.

The researchers examined previous studies to determine if GnRH agonist therapy could improve pregnancy outcomes for women with endometriosis. They sought to uncover if this therapeutic oasis could offer a pathway to successful conception for those struggling with fertility challenges.

The Potential of GnRH Agonist Therapy

While the review acknowledged that long-term GnRH agonist therapy may have a positive impact on pregnancy outcomes, the evidence remains inconclusive. Further research is needed to definitively assess the benefits and risks of this treatment for women with endometriosis undergoing IVF or ICSI.

Navigating the Path to Parenthood

Women with endometriosis often face an uphill battle on their journey to parenthood. It's important for them to work closely with their doctors to explore all treatment options, including GnRH agonist therapy, and weigh the potential benefits against the risks. The path to parenthood may be long and winding, but with the right support and guidance, they can navigate the desert of fertility challenges and reach their destination.

Dr.Camel's Conclusion

This review highlights the complexities of infertility treatment for women with endometriosis. While GnRH agonist therapy may hold promise, the evidence is still developing. It's crucial for women struggling with endometriosis to work closely with their doctors to find the right treatment plan, ensuring they receive the support and guidance they need on their journey to parenthood.

Date :
  1. Date Completed 2020-04-16
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

31747470

DOI: Digital Object Identifier

PMC6867786

Related Literature

Article Analysis
・Effective treatment of endometriosis
SNS
PICO Info
in preparation
Languages

English

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